Carcinoma renale bilaterale multiplo familiare: strategia clinica e tattica chirurgica.

Translated title of the contribution: Familial multiple bilateral carcinoma of the kidney: clinical strategy and surgical approach

A. Mandressi, C. Buizza, A. Assi, L. Solbiati, D. Antonelli, P. Allaria, S. Greco, V. Cioffi

Research output: Contribution to journalArticlepeer-review

Abstract

A case of familiar bilateral multicentric RCC in a young woman is an ideal model to evaluate preoperative and intraoperative diagnostic and surgical tools in order to achieve two distinct goals: the oncologic radicalness and the renal function preserved. Radical bilateral nephrectomy, the renal hypothermia by perfusion of both kidneys, the bench high resolution sonography of parenchyma, the choose of one kidney suitable for conservative surgery, the resection of suspect lesions with intraoperative pathology, the reconstructive bench surgery, the autotransplantation, are the steps accurately performed with particular concern to eradication of all the tumoral lesions present in the kidneys. The results confirm that renal function has been preserved with this method. Radicalness should be appointed by a longlasting follow up. However, as it is discussed, conservative surgery, when accurately performed can give results not different from radical demolitive surgery. In this paper tools to improve diagnostic and therapeutic methods are described in order to increase the diagnostic accuracy and the therapeutic efficacy. The possibility that this multiple RCC can be a part of the abnormalities occurring in the Von Hippel-Lindau syndrome does not change the surgical approach, being the RCC the worst prognostic factor of the syndrome.

Translated title of the contributionFamilial multiple bilateral carcinoma of the kidney: clinical strategy and surgical approach
Original languageItalian
Pages (from-to)539-549
Number of pages11
JournalArchivio Italiano di Urologia e Andrologia
Volume65
Issue number5
Publication statusPublished - Oct 1993

ASJC Scopus subject areas

  • Nephrology
  • Urology

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