We describe a previously unreported Italian family with ADLTE in which there are two affected individuals. In both of them seizures were characterized by psychic aura without auditory phenomena. A novel mutation in the leucine-rich, glioma-inactivated 1(LGI1) gene (c219C>T) was found. This observation remarks that LGI1 mutations may be found even in familial TLEs without auditory seizures.
|Translated title of the contribution||Familial temporal lobe epilepsy with dominant psychic semiology associated to a novel mutation in LGI1 gene|
|Number of pages||2|
|Journal||Bollettino - Lega Italiana contro l'Epilessia|
|Publication status||Published - Apr 2010|
ASJC Scopus subject areas
- Clinical Neurology