Family history of cancer, its combination with smoking and drinking, and risk of squamous cell carcinoma of the esophagus

Werner Garavello, Eva Negri, Renato Talamini, Fabio Levi, Paola Zambon, Luigino Dal Maso, Cristina Bosetti, Silvia Franceschi, Carlo La Vecchia

Research output: Contribution to journalArticle


We analyzed the association between history of cancer in first-degree relatives and the risk of squamous cell carcinoma of the esophagus (SCCE) using data from three case-control studies conducted in Italy and Switzerland on 805 incident, histologically confirmed SCCE, and 3,461 hospital controls. The alcohol- and tobacco-adjusted odds ratio (OR) for a family history of esophageal cancer was 3.2 [95% confidence interval (CI), 1.7-6.2], and the OR was higher when the affected relative was a brother or was diagnosed at age

Original languageEnglish
Pages (from-to)1390-1393
Number of pages4
JournalCancer Epidemiology Biomarkers and Prevention
Issue number6
Publication statusPublished - Jun 2005


ASJC Scopus subject areas

  • Epidemiology
  • Oncology

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