Objective: The authors investigated the relationships between hypersensitivity to CO 2 and familial-genetic risk for panic disorder in patients with panic disorder. Method: Morbidity risks for panic disorder were calculated for families of 203 patients with panic disorder, each of whom was challenged with 35% CO 2. Results: Patients who reacted with a positive response to the 35% CO 2 challenge showed a genetic risk for panic disorder (morbidity risk = 14.4%) that was significantly higher than that for patients who did not react (morbidity risk=3.9%). Conclusions: These findings support the idea that hypersensitivity to CO 2 might be associated with a subtype of panic disorder specifically related to a greater familial loading.
|Number of pages||5|
|Journal||American Journal of Psychiatry|
|Publication status||Published - Aug 1996|
ASJC Scopus subject areas
- Psychiatry and Mental health