Famotidine has no significant effect on gonadal function in man

V. Savarino, M. Giusti, P. Scalabrini, D. Bessarione, M. R. Magnolia, G. Percario, G. Celle

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

The effect of a single bedtime dose of famotidine 40 mg on gonadal function was studied in 8 male duodenal ulcer patients. The drug was orally administered for 4 week. Our results show that this new H2 blocker influences basal and stimulated serum levels of neither testosterone nor gonadotrophins (LH, fsh). Besides, no significant variations were observed before and after famotidine treatment in seminal fluid characteristics evaluated in 5 out of 8 cases. It can be concluded that famotidine appears to leave gonadal function unaffected in man.

Original languageEnglish
Pages (from-to)19-22
Number of pages4
JournalGastroenterologie Clinique et Biologique
Volume12
Issue number1
Publication statusPublished - 1988

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Famotidine
Duodenal Ulcer
Gonadotropins
Testosterone
Serum
Pharmaceutical Preparations
Therapeutics

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Savarino, V., Giusti, M., Scalabrini, P., Bessarione, D., Magnolia, M. R., Percario, G., & Celle, G. (1988). Famotidine has no significant effect on gonadal function in man. Gastroenterologie Clinique et Biologique, 12(1), 19-22.

Famotidine has no significant effect on gonadal function in man. / Savarino, V.; Giusti, M.; Scalabrini, P.; Bessarione, D.; Magnolia, M. R.; Percario, G.; Celle, G.

In: Gastroenterologie Clinique et Biologique, Vol. 12, No. 1, 1988, p. 19-22.

Research output: Contribution to journalArticle

Savarino, V, Giusti, M, Scalabrini, P, Bessarione, D, Magnolia, MR, Percario, G & Celle, G 1988, 'Famotidine has no significant effect on gonadal function in man', Gastroenterologie Clinique et Biologique, vol. 12, no. 1, pp. 19-22.
Savarino V, Giusti M, Scalabrini P, Bessarione D, Magnolia MR, Percario G et al. Famotidine has no significant effect on gonadal function in man. Gastroenterologie Clinique et Biologique. 1988;12(1):19-22.
Savarino, V. ; Giusti, M. ; Scalabrini, P. ; Bessarione, D. ; Magnolia, M. R. ; Percario, G. ; Celle, G. / Famotidine has no significant effect on gonadal function in man. In: Gastroenterologie Clinique et Biologique. 1988 ; Vol. 12, No. 1. pp. 19-22.
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