FARMAPRICE: A Pharmacogenetic Clinical decision support system for precise and Cost-Effective Therapy

Rossana Roncato, Lisa Dal Cin, Silvia Mezzalira, Francesco Comello, Elena De Mattia, Alessia Bignucolo, Lorenzo Giollo, Simone D’Errico, Antonio Gulotta, Luca Emili, Vincenzo Carbone, Michela Guardascione, Luisa Foltran, Giuseppe Toffoli, Erika Cecchin

Research output: Contribution to journalArticle

Abstract

Pharmacogenetic (PGx) guidelines for the precise dosing and selection of drugs remain poorly implemented in current clinical practice. Among the barriers to the implementation process is the lack of clinical decision support system (CDSS) tools to aid health providers in managing PGx information in the clinical context. The present study aimed to describe the first Italian endeavor to develop a PGx CDSS, called FARMAPRICE. FARMAPRICE prototype was conceived for integration of patient molecular data into the clinical prescription process in the Italian Centro di Riferimento Oncologico (CRO)-Aviano Hospital. It was developed through a coordinated partnership between two high-tech companies active in the computerization of the Italian healthcare system. Introducing FARMAPRICE into the clinical setting can aid physicians in prescribing the most efficacious and cost-effective pharmacological therapy available.

Original languageEnglish
Article number276
Number of pages13
JournalGenes
Volume10
Issue number4
DOIs
Publication statusPublished - Apr 2019

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Keywords

  • CDSS
  • Implementation
  • Pharmacogenetics

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)

Cite this

Roncato, R., Cin, L. D., Mezzalira, S., Comello, F., De Mattia, E., Bignucolo, A., Giollo, L., D’Errico, S., Gulotta, A., Emili, L., Carbone, V., Guardascione, M., Foltran, L., Toffoli, G., & Cecchin, E. (2019). FARMAPRICE: A Pharmacogenetic Clinical decision support system for precise and Cost-Effective Therapy. Genes, 10(4), [276]. https://doi.org/10.3390/genes10040276