Fat grafting for breast cancer patients: From basic science to clinical studies

R. Gennari, G. Griguolo, Maria Vittoria Dieci, V. Guarneri, B. Tavaniello, A. Sibilio, P. Conte

Research output: Contribution to journalArticlepeer-review

Abstract

Fat grafting in the surgical treatment of breast cancer has become popular in a short period of time because of the rising expectations of good esthetic results by the patients as well as the simplicity of the technique; however, the oncological safety for breast cancer patients remains a matter of debate. The procedure raises many questions considering that recent in-vitro studies have shown that fat grafting could promote tumor recurrence through diverse mechanisms, or even facilitate distant metastasis. We present a review of the currently available experimental and clinical data in order to describe and discuss patient selection criteria following breast cancer surgery.

Original languageEnglish
Pages (from-to)1088-1102
Number of pages15
JournalEuropean Journal of Surgical Oncology
Volume42
Issue number8
DOIs
Publication statusPublished - Aug 2016

Keywords

  • ASCs (adipose stem cells)
  • Breast cancer
  • Fat grafting
  • Lipoffiling
  • Oncological outcome
  • Safety

ASJC Scopus subject areas

  • Oncology
  • Surgery

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