TY - JOUR
T1 - Fatal cerebral haemorrhage after liver transplantation in a patient with transthyretin variant (gly53glu) amyloidosis
AU - Carolis, P.
AU - Galeotti, M.
AU - Ficarra, G.
AU - Masetti, M.
AU - Grimaldi, D.
AU - Cortelli, P.
PY - 2006/11
Y1 - 2006/11
N2 - Transthyretin (TTR) amyloidosis is a form of systemic amyloidosis caused by an amyloidogenetic TTR variant. The most common mutant forms of TTR are mainly produced by the liver and therefore orthotopic liver transplantation (OLT) is currently accepted as the only known curative treatment. We describe the clinical and pathological features of a patient with TTR variant (gly53glu) with TTR amyloid infiltration of the leptomeningeal vessels in whom fatal cerebral haemorrhage occurred two months after OLT, soon after severe viral pneumonia.
AB - Transthyretin (TTR) amyloidosis is a form of systemic amyloidosis caused by an amyloidogenetic TTR variant. The most common mutant forms of TTR are mainly produced by the liver and therefore orthotopic liver transplantation (OLT) is currently accepted as the only known curative treatment. We describe the clinical and pathological features of a patient with TTR variant (gly53glu) with TTR amyloid infiltration of the leptomeningeal vessels in whom fatal cerebral haemorrhage occurred two months after OLT, soon after severe viral pneumonia.
KW - Cerebral haemorrhage
KW - Liver transplantation
KW - Transthyretin amyloidosis
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U2 - 10.1007/s10072-006-0709-5
DO - 10.1007/s10072-006-0709-5
M3 - Article
C2 - 17122946
AN - SCOPUS:37849185956
VL - 27
SP - 352
EP - 354
JO - Neurological Sciences
JF - Neurological Sciences
SN - 1590-1874
IS - 5
ER -