Fatty Acids in Nephrotic Syndrome and Chronic Kidney Disease

Stefano Turolo, Alberto Edefonti, Marie Louise Syren, Franca Marangoni, William Morello, Carlo Agostoni, Giovanni Montini

Research output: Contribution to journalArticle

Abstract

The role of fatty acids (FAs) in inflammation and in the related chronic diseases has been demonstrated. However, there is a lack of consistent and agreed knowledge about the role of FA profile and renal physiology and pathology, most articles focusing on the effect of polyunsaturated FAs supplementation, without considering the impact of basal FA metabolism on the efficacy of the supplementation. Here, we have summarized the specific literature concerning the assessment of circulating FA in 2 renal diseases, namely nephrotic syndrome and chronic kidney disease, also under hemodialytic treatment, and have received the most significant contributions in the last years. The effects of changes of FA profile and metabolism and the possible involvement of polyunsaturated FA metabolites in raising and modulating inflammation are discussed.

Original languageEnglish
Pages (from-to)145-155
JournalJournal of Renal Nutrition
Volume28
Issue number3
DOIs
Publication statusPublished - 2018

    Fingerprint

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics
  • Nephrology

Cite this