Feasibility and Surgical Outcome in Obese Versus Nonobese Patients Undergoing Laparoendoscopic Single-site Hysterectomy: A Multicenter Case-control Study

Francesco Fanfani, David M. Boruta, Amanda N. Fader, Enrico Vizza, Withfiel B. Growdon, Cristina L. Kushnir, Giacomo Corrado, Giovanni Scambia, Luigi C. Turco, Anna Fagotti

Research output: Contribution to journalArticle


Objective: To assess the feasibility and perioperative outcomes of laparoendoscopic single-site (LESS) hysterectomy in obese and nonobese women. Design: A multicentric retrospective case-control study (Canadian Task Force II-2). Setting: Catholic University of the Sacred Heart and National Cancer Institute "Regina Elena" (Rome, Italy), Massachusetts General Hospital (Boston, MD), and Johns Hopkins Hospital (Baltimore, MD). Patients: From July 2009 to April 2013, 120 women underwent LESS hysterectomy. Five women (8%) were excluded from the analysis. The remaining 115 women were divided into 2 groups: obese (n=43, body mass index [BMI] 2) and nonobese (n=72, BMI 2). Interventions: Total LESS hysterectomies for malignant and premalignant uterine disease or at least for prophylactic intent were performed. Measurements and Main Results: No statistical differences regarding perioperative outcomes were observed between the 2 groups. Conversion to standard laparoscopy occurred in 2 obese (5%) and 2 (5%) nonobese women (p=62). Conversion to laparotomy occurred in 1 obese (2.3%) and 3 (4.2%) nonobese women (p=212). The median operative time was 115minutes (range, 48-300minutes) in obese and 114minutes (range, 55-342minutes) in nonobese women (p=787). The intraoperative complication rate was 11.6% and 9.6% in obese and nonobese women, respectively (p=712). The early postoperative complication rate was 6.9% in obese and 4.1% in nonobese women (p=516). Conclusion: Despite the fact that the present analysis was performed in a relatively small group of patients, this study suggests that obesity (BMI

Original languageEnglish
Pages (from-to)456-461
Number of pages6
JournalJournal of Minimally Invasive Gynecology
Issue number3
Publication statusPublished - Mar 1 2015



  • Hysterectomy
  • Laparoendoscopic single-site surgery
  • Laparoscopy
  • Obesity
  • Single site

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Medicine(all)

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