Abstract
Alterations in lipid metabolism are a possible consequence of highly active antiretroviral therapies (HAART) for human immunodeficiency virus (HIV)-positive patients with consequent increase of cardiovascular risk. In this context we hypothesized that both acquired immunodeficiency syndrome (AIDS) and HAART might be associated to alterations in autonomic cardiovascular regulation. In this preliminary investigation we enrolled a total of 66 men, subdivided in two groups, 33 HIV-positive patients, and 33 healthy controls, and we tested the hypothesis that heart rate variability (HRV) of HIV positive patients can be assessed with a transtelephonic approach from the HIV clinic: 100% of the total of electrocardiograms (ECG) recordings that were sent from the distant site were successfully received and analyzed. Evaluation of the signal was subsequently performed in the centralized laboratory, and consisted in extracting the RR interval variability (RRV) series and afterward subjecting it to autoregressive spectral analysis. This study shows the feasibility of obtaining, from personnel without specific training, adequate RR variability data for further spectral analysis form a distant specialized autonomic laboratory. This feature is of critical importance in the context of possible large-scale application of this simple telemedicine approach.
| Original language | English |
|---|---|
| Pages (from-to) | 557-563 |
| Number of pages | 7 |
| Journal | Telemedicine journal and e-health : the official journal of the American Telemedicine Association |
| Volume | 13 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - Oct 2007 |
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ASJC Scopus subject areas
- Medicine(all)
- Bioengineering
- Media Technology
- Nursing(all)
Cite this
Feasibility of assessing autonomic dysregulation at a distance : the case of the HIV-positive patient. / Malacarne, Mara; Cargnel, Antonietta; Lucini, Daniela; Pizzinelli, Paolo; Porta, Alberto; Pagani, Massimo.
In: Telemedicine journal and e-health : the official journal of the American Telemedicine Association, Vol. 13, No. 5, 10.2007, p. 557-563.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Feasibility of assessing autonomic dysregulation at a distance
T2 - the case of the HIV-positive patient.
AU - Malacarne, Mara
AU - Cargnel, Antonietta
AU - Lucini, Daniela
AU - Pizzinelli, Paolo
AU - Porta, Alberto
AU - Pagani, Massimo
PY - 2007/10
Y1 - 2007/10
N2 - Alterations in lipid metabolism are a possible consequence of highly active antiretroviral therapies (HAART) for human immunodeficiency virus (HIV)-positive patients with consequent increase of cardiovascular risk. In this context we hypothesized that both acquired immunodeficiency syndrome (AIDS) and HAART might be associated to alterations in autonomic cardiovascular regulation. In this preliminary investigation we enrolled a total of 66 men, subdivided in two groups, 33 HIV-positive patients, and 33 healthy controls, and we tested the hypothesis that heart rate variability (HRV) of HIV positive patients can be assessed with a transtelephonic approach from the HIV clinic: 100% of the total of electrocardiograms (ECG) recordings that were sent from the distant site were successfully received and analyzed. Evaluation of the signal was subsequently performed in the centralized laboratory, and consisted in extracting the RR interval variability (RRV) series and afterward subjecting it to autoregressive spectral analysis. This study shows the feasibility of obtaining, from personnel without specific training, adequate RR variability data for further spectral analysis form a distant specialized autonomic laboratory. This feature is of critical importance in the context of possible large-scale application of this simple telemedicine approach.
AB - Alterations in lipid metabolism are a possible consequence of highly active antiretroviral therapies (HAART) for human immunodeficiency virus (HIV)-positive patients with consequent increase of cardiovascular risk. In this context we hypothesized that both acquired immunodeficiency syndrome (AIDS) and HAART might be associated to alterations in autonomic cardiovascular regulation. In this preliminary investigation we enrolled a total of 66 men, subdivided in two groups, 33 HIV-positive patients, and 33 healthy controls, and we tested the hypothesis that heart rate variability (HRV) of HIV positive patients can be assessed with a transtelephonic approach from the HIV clinic: 100% of the total of electrocardiograms (ECG) recordings that were sent from the distant site were successfully received and analyzed. Evaluation of the signal was subsequently performed in the centralized laboratory, and consisted in extracting the RR interval variability (RRV) series and afterward subjecting it to autoregressive spectral analysis. This study shows the feasibility of obtaining, from personnel without specific training, adequate RR variability data for further spectral analysis form a distant specialized autonomic laboratory. This feature is of critical importance in the context of possible large-scale application of this simple telemedicine approach.
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U2 - 10.1089/tmj.2006.0092
DO - 10.1089/tmj.2006.0092
M3 - Article
C2 - 17999617
AN - SCOPUS:38349174421
VL - 13
SP - 557
EP - 563
JO - Telemedicine Journal and e-Health
JF - Telemedicine Journal and e-Health
SN - 1530-5627
IS - 5
ER -