Febrile infection-related epilepsy syndrome (FIRES): Does duration of anesthesia affect outcome?

Uri Kramer, Ching Shiang Chi, Kuang Lin Lin, Nicola Specchio, Mustafa Sahin, Heather Olson, Gerhard Kluger, Andreas Van Baalen

Research output: Contribution to journalArticlepeer-review


We conducted a retrospective multicenter study on children who had been included in eight studies published between November 2001 and July 2010 to explore the correlations between burst-suppression coma (BSC) with outcome in febrile infection-related epilepsy syndrome (FIRES). The 77 enrolled patients presented with prolonged refractory status epilepticus. BSC was induced in 46 patients. Cognitive levels at follow-up were significantly associated with duration of a BSC (p = 0.005). The outcome of FIRES is poor. Treatment by inducing a prolonged BSC was associated with a worse cognitive outcome.

Original languageEnglish
Pages (from-to)28-30
Number of pages3
Issue numberSUPPL. 8
Publication statusPublished - Oct 2011


  • Children
  • Epilepsy
  • Refractory
  • Status epilepticus

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology


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