Fecal calprotectin to detect inflammatory bowel disease in juvenile idiopathic arthritis

Giovanna Ferrara, Serena Pastore, Lara Sancin, Lucio Torelli, Oriano Radillo, Matteo Bramuzzo, Chiara Bibalo, Alberto Tommasini, Alessandro Ventura, Andrea Taddio

Research output: Contribution to journalArticlepeer-review

Abstract

Objective. This study aimed to test fecal calprotectin (FC) as a screening tool to identify inflammatory bowel disease (IBD) among patients with juvenile idiopathic arthritis (JIA). Methods. FC level < 100 g/kg was considered normal. Patients with 2 consecutive FC dosage . 100 g/kg underwent endoscopic evaluation. Results. There were 113 patients with JIA enrolled. FC was raised in 7 patients out of 113. All patients had IBD. In 3/7 patients, high FC levels were the only sign consistent with IBD. Conclusion. FC is a useful, economical, and noninvasive diagnostic tool to identify JIA patients with underlying IBD.

Original languageEnglish
Pages (from-to)1418-1421
Number of pages4
JournalJournal of Rheumatology
Volume45
Issue number10
DOIs
Publication statusPublished - Oct 1 2018

Keywords

  • CHRONIC ARTHRITIS
  • Crohn DISEASE
  • FECAL CALPROTECTIN
  • INFLAMMATORY BOWEL DISEASE
  • JUVENILE IDIOPATHIC ARTHRITIS

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

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