Abstract
PURPOSE: This study was designed to assess the role of fecal lactoferrin and calprotectin as markers of intestinal inflammation in patients with Crohn's disease who have undergone ileocolonic resection. METHODS: Sixty-three patients who had undergone ileocolonic resection for Crohn's disease with a median follow-up of 40.5 (range, 5-102) months were enrolled. Clinical examination and blood test were performed, and fecal lactoferrin and calprotectin levels were dosed. The predictors for fecal lactoferrin and calprotectin levels that resulted to be significant at the univariate analyses were included in two multiple regression analysis models. RESULTS: The mean lactoferrin level was 21±3.9 μg/g and the mean calprotectin fecal level was 247±22.7 ng/ml. C-reactive protein levels (P
| Original language | English |
|---|---|
| Pages (from-to) | 861-869 |
| Number of pages | 9 |
| Journal | Diseases of the Colon and Rectum |
| Volume | 50 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Jun 2007 |
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Keywords
- C-reactive protein
- Calprotectin
- Crohn's disease
- Lactoferrin
- Recurrence
ASJC Scopus subject areas
- Gastroenterology
Cite this
Fecal lactoferrin and calprotectin after ileocolonic resection for Crohn's disease. / Scarpa, Marco; D'Incà, Renata; Basso, Daniela; Ruffolo, Cesare; Polese, Lino; Bertin, Eugenia; Luise, Alessia; Frego, Mauro; Plebani, Mario; Sturniolo, Giacomo C.; D'Amico, Davide F.; Angriman, Imerio.
In: Diseases of the Colon and Rectum, Vol. 50, No. 6, 06.2007, p. 861-869.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Fecal lactoferrin and calprotectin after ileocolonic resection for Crohn's disease
AU - Scarpa, Marco
AU - D'Incà, Renata
AU - Basso, Daniela
AU - Ruffolo, Cesare
AU - Polese, Lino
AU - Bertin, Eugenia
AU - Luise, Alessia
AU - Frego, Mauro
AU - Plebani, Mario
AU - Sturniolo, Giacomo C.
AU - D'Amico, Davide F.
AU - Angriman, Imerio
PY - 2007/6
Y1 - 2007/6
N2 - PURPOSE: This study was designed to assess the role of fecal lactoferrin and calprotectin as markers of intestinal inflammation in patients with Crohn's disease who have undergone ileocolonic resection. METHODS: Sixty-three patients who had undergone ileocolonic resection for Crohn's disease with a median follow-up of 40.5 (range, 5-102) months were enrolled. Clinical examination and blood test were performed, and fecal lactoferrin and calprotectin levels were dosed. The predictors for fecal lactoferrin and calprotectin levels that resulted to be significant at the univariate analyses were included in two multiple regression analysis models. RESULTS: The mean lactoferrin level was 21±3.9 μg/g and the mean calprotectin fecal level was 247±22.7 ng/ml. C-reactive protein levels (P
AB - PURPOSE: This study was designed to assess the role of fecal lactoferrin and calprotectin as markers of intestinal inflammation in patients with Crohn's disease who have undergone ileocolonic resection. METHODS: Sixty-three patients who had undergone ileocolonic resection for Crohn's disease with a median follow-up of 40.5 (range, 5-102) months were enrolled. Clinical examination and blood test were performed, and fecal lactoferrin and calprotectin levels were dosed. The predictors for fecal lactoferrin and calprotectin levels that resulted to be significant at the univariate analyses were included in two multiple regression analysis models. RESULTS: The mean lactoferrin level was 21±3.9 μg/g and the mean calprotectin fecal level was 247±22.7 ng/ml. C-reactive protein levels (P
KW - C-reactive protein
KW - Calprotectin
KW - Crohn's disease
KW - Lactoferrin
KW - Recurrence
UR - http://www.scopus.com/inward/record.url?scp=34249900168&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34249900168&partnerID=8YFLogxK
U2 - 10.1007/s10350-007-0225-6
DO - 10.1007/s10350-007-0225-6
M3 - Article
VL - 50
SP - 861
EP - 869
JO - Diseases of the Colon and Rectum
JF - Diseases of the Colon and Rectum
SN - 0012-3706
IS - 6
ER -