Female precocious puberty, obesity and polycystic-like ovaries

C. Battaglia, P. De Iaco, L. Iughetti, F. Mancini, N. Persico, A. D. Genazzani, A. Volpe, D. De Aloysio

Research output: Contribution to journalArticle


Objective: To evaluate the characteristics of obese girls with gonadotropin releasing hormone-dependent precocious puberty with and without polycystic-like ovaries. Methods: Forty-seven overweight (> 75th centile of the Italian reference data) girls with a diagnosis of isosexual precocious puberty underwent auxological analysis, hormonal assay and utero-ovarian sonographic and Doppler evaluation. On the basis of sonography the patients were subdivided into two groups, girls presenting normal ovaries (Group I; n = 31) and those with polycystic-like ovaries (Group II; n = 16). Results: The mean body weight was significantly higher (P = 0.003) in Group II than it was in Group I. In addition, the patients with polycystic-like ovaries fell within our definition of superobese (≥ 97th centile of the Italian reference data) in 44% of cases. The uterine and ovarian volumes were significantly greater in Group II compared with Group I patients. The Doppler evaluation showed intraparenchymal ovarian vascularization and low downstream impedance to flow in all patients in Group II. Conclusions: Girls with precocious puberty and polycystic ovaries, compared with those without polycystic ovaries, have a higher incidence of body weight exceeding the 85th centile of the Italian reference data (obesity).

Original languageEnglish
Pages (from-to)651-657
Number of pages7
JournalUltrasound in Obstetrics and Gynecology
Issue number6
Publication statusPublished - Nov 2005


  • Doppler
  • Obesity
  • PCO
  • Puberty
  • Ultrasound

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology
  • Reproductive Medicine
  • Acoustics and Ultrasonics

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    Battaglia, C., De Iaco, P., Iughetti, L., Mancini, F., Persico, N., Genazzani, A. D., Volpe, A., & De Aloysio, D. (2005). Female precocious puberty, obesity and polycystic-like ovaries. Ultrasound in Obstetrics and Gynecology, 26(6), 651-657. https://doi.org/10.1002/uog.2596