TY - JOUR
T1 - Female sex and the use of anti-allergic agents increase the risk of developing cutaneous rash associated with nevirapine therapy
AU - Antinori, Andrea
AU - Baldini, Francesco
AU - Girardi, Enrico
AU - Cingolani, Antonella
AU - Zaccarelli, Mauro
AU - Di Giambenedetto, Simona
AU - Barracchini, Annalisa
AU - De Longis, Patrizio
AU - Murri, Rita
AU - Tozzi, Valerio
AU - Ammassari, Adriana
AU - Rizzo, Maria Gabriella
AU - Ippolito, Giuseppe
AU - De Luca, Andrea
PY - 2001/8/17
Y1 - 2001/8/17
N2 - To identify factors associated with cutaneous rash, we performed a retrospective multicentre analysis of HIV outpatients starting a highly active antiretroviral therapy regimen containing nevirapine. A total of 62 cutaneous adverse events were observed in 429 patients. Rash hazard was increased in women, by the prophylactic use of glucocorticoids or antihistaminics, and was reduced by escalating the initial dose of nevirapine. Women receiving glucocorticoids had a 3 month cumulative probability of rash of 0.41.
AB - To identify factors associated with cutaneous rash, we performed a retrospective multicentre analysis of HIV outpatients starting a highly active antiretroviral therapy regimen containing nevirapine. A total of 62 cutaneous adverse events were observed in 429 patients. Rash hazard was increased in women, by the prophylactic use of glucocorticoids or antihistaminics, and was reduced by escalating the initial dose of nevirapine. Women receiving glucocorticoids had a 3 month cumulative probability of rash of 0.41.
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U2 - 10.1097/00002030-200108170-00018
DO - 10.1097/00002030-200108170-00018
M3 - Article
C2 - 11504993
AN - SCOPUS:0035903010
VL - 15
SP - 1579
EP - 1581
JO - AIDS
JF - AIDS
SN - 0269-9370
IS - 12
ER -