Fenoldopamin in der Herzchirurgie

G. Landoni; D. Poli; T. Bove

doi:10.1007/s11789-006-0046-5

Fenoldopamin in der Herzchirurgie

Translated title of the contribution: Fenoldopamin in cardiac surgery

G. Landoni, D. Poli, T. Bove

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

Fenoldopam mesylate is a useful antihypertensive and diuretic drug. In this review, we examine the evidence based medicine wheter to use fenoldopam in cardiac surgery patients and/or in critically ill patients with or at risk for acute renal failure (ARF). We conclude that from published studies it seems that fenoldopam could be beneficial if a prolonged infusion is performed starting early in the process of ARF in critically ill patients. Unfortunately there is still virtually no definitive evidence of efficacy, especially in cardiac surgery patients. A large, multicenter, randomized, controlled trial (RCT) is needed to confirm the promising but conflicting findings of this drug.

Translated title of the contribution	Fenoldopamin in cardiac surgery
Original language	German
Journal	Clinical Research in Cardiology Supplements
Volume	2
Issue number	SUPL.1
DOIs	https://doi.org/10.1007/s11789-006-0046-5
Publication status	Published - 2007

Keywords

acute renal failure
cardiac surgery
diuretics
fenoldopam
renal replacement therapy

ASJC Scopus subject areas

Molecular Biology
Radiology Nuclear Medicine and imaging
Structural Biology

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AU - Poli, D.

AU - Bove, T.

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AB - Fenoldopam mesylate is a useful antihypertensive and diuretic drug. In this review, we examine the evidence based medicine wheter to use fenoldopam in cardiac surgery patients and/or in critically ill patients with or at risk for acute renal failure (ARF). We conclude that from published studies it seems that fenoldopam could be beneficial if a prolonged infusion is performed starting early in the process of ARF in critically ill patients. Unfortunately there is still virtually no definitive evidence of efficacy, especially in cardiac surgery patients. A large, multicenter, randomized, controlled trial (RCT) is needed to confirm the promising but conflicting findings of this drug.

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KW - diuretics

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KW - renal replacement therapy

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Fenoldopamin in der Herzchirurgie

Abstract

Keywords

ASJC Scopus subject areas

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