Fenoldopamin in der Herzchirurgie

Translated title of the contribution: Fenoldopamin in cardiac surgery

G. Landoni, D. Poli, T. Bove

Research output: Contribution to journalArticle

Abstract

Fenoldopam mesylate is a useful antihypertensive and diuretic drug. In this review, we examine the evidence based medicine wheter to use fenoldopam in cardiac surgery patients and/or in critically ill patients with or at risk for acute renal failure (ARF). We conclude that from published studies it seems that fenoldopam could be beneficial if a prolonged infusion is performed starting early in the process of ARF in critically ill patients. Unfortunately there is still virtually no definitive evidence of efficacy, especially in cardiac surgery patients. A large, multicenter, randomized, controlled trial (RCT) is needed to confirm the promising but conflicting findings of this drug.

Original languageGerman
JournalClinical Research in Cardiology Supplements
Volume2
Issue numberSUPL.1
DOIs
Publication statusPublished - 2007

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Keywords

  • acute renal failure
  • cardiac surgery
  • diuretics
  • fenoldopam
  • renal replacement therapy

ASJC Scopus subject areas

  • Molecular Biology
  • Radiology Nuclear Medicine and imaging
  • Structural Biology

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