Fertility preservation in women with cervical cancer

Edgardo Somigliana, Giorgia Mangili, Fabio Martinelli, Stefania Noli, Francesca Filippi, Alice Bergamini, Luca Bocciolone, Barbara Buonomo, Fedro Peccatori

Research output: Contribution to journalReview articlepeer-review


Fertility preservation in women with cervical cancer is a demanding but evolving issue. Some remarkable achievements have been reached, in particular the improvement of primary and secondary prevention and the broadening of the indications for conservative surgery up to FIGO 2018 stage IB2. Natural pregnancy rate and the rate of obstetrics complications following conservative approach is satisfactory even if not optimal. On the other hand, the use of classic strategies for fertility preservation such as oocytes or ovarian cortex freezing is extremely limited, being the uterus compromised by treatment in a high proportion of cases. In fact, the availability of uterine surrogacy can play a role in the counseling and the decision-making process. The recent advent of uterus transplantation is fascinating but, at present, cannot be viewed as a realistic solution.

Original languageEnglish
Pages (from-to)103092
JournalCritical Reviews in Oncology/Hematology
Publication statusPublished - Oct 2020


  • Counseling
  • Cryopreservation
  • Female
  • Fertility Preservation
  • Humans
  • Oocytes
  • Ovary
  • Pregnancy
  • Uterine Cervical Neoplasms


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