Fibrinogen and factor VII as risk factors for ischemic heart disease

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High plasmatic levels of factor VII and fibrinogen are useful predictors of the risk of ischemic heart disease, but have not yet been included in the laboratory profile for the assessment of this risk. This is because it is not known which method is more informative and practical, and also because of the poor standardization of the assays currently made. Over recent years, the Hemostasis Subcommittee of the 'Comitato Italiano per la Standardizzazione dei Metodi in Ematologia e Laboratorio' (CISMeL) carried out and published collaborative studies aiming to assess the performance characteristics of fibrinogen and factor VII assays. The aim of this paper is to give an account of these activities, to review the problems and to suggest possible solutions.

Original languageEnglish
Pages (from-to)262-265
Number of pages4
JournalEuropean Journal of Laboratory Medicine
Issue number3
Publication statusPublished - 1995

ASJC Scopus subject areas

  • Medicine(all)


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