Abstract
Fourteen patients with essential mixed cryoglobulinemia were studied. The relevance of fibronectin (FN) in cryoprecipitation seems to be of relative importance since only two thirds of the cryoprecipitates have a higher cryocrit level when FN is present. On the other hand, the other samples show a lower precipitating activity after plasma heating at 60°C. This reduction may reflect either a structural FN modification by heating or the denaturation of other cryoprecipitating molecules. It is possible, even if not necessary, that at least in vitro FN plays a role in the cryoprecipitate formation.
Original language | English |
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Pages (from-to) | 321-326 |
Number of pages | 6 |
Journal | La Ricerca in Clinica e in Laboratorio |
Volume | 16 |
Issue number | 2 |
DOIs | |
Publication status | Published - Apr 1986 |
Keywords
- Cryoprecipitation
- Essential mixed cryoglobulinemia
- Fibrin
- Fibrinogen
- Fibrinogen degradation products
- Fibronectin
ASJC Scopus subject areas
- Clinical Biochemistry