Fibronectin and cryoprecipitation

Sebastiano Garelli, Pier Luigi Meroni, Franco Montani, Fulvio Invernizzi

Research output: Contribution to journalArticlepeer-review

Abstract

Fourteen patients with essential mixed cryoglobulinemia were studied. The relevance of fibronectin (FN) in cryoprecipitation seems to be of relative importance since only two thirds of the cryoprecipitates have a higher cryocrit level when FN is present. On the other hand, the other samples show a lower precipitating activity after plasma heating at 60°C. This reduction may reflect either a structural FN modification by heating or the denaturation of other cryoprecipitating molecules. It is possible, even if not necessary, that at least in vitro FN plays a role in the cryoprecipitate formation.

Original languageEnglish
Pages (from-to)321-326
Number of pages6
JournalLa Ricerca in Clinica e in Laboratorio
Volume16
Issue number2
DOIs
Publication statusPublished - Apr 1986

Keywords

  • Cryoprecipitation
  • Essential mixed cryoglobulinemia
  • Fibrin
  • Fibrinogen
  • Fibrinogen degradation products
  • Fibronectin

ASJC Scopus subject areas

  • Clinical Biochemistry

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