Fibronectin and cryoprecipitation

Sebastiano Garelli, Pier Luigi Meroni, Franco Montani, Fulvio Invernizzi

Research output: Contribution to journalArticlepeer-review


Fourteen patients with essential mixed cryoglobulinemia were studied. The relevance of fibronectin (FN) in cryoprecipitation seems to be of relative importance since only two thirds of the cryoprecipitates have a higher cryocrit level when FN is present. On the other hand, the other samples show a lower precipitating activity after plasma heating at 60°C. This reduction may reflect either a structural FN modification by heating or the denaturation of other cryoprecipitating molecules. It is possible, even if not necessary, that at least in vitro FN plays a role in the cryoprecipitate formation.

Original languageEnglish
Pages (from-to)321-326
Number of pages6
JournalLa Ricerca in Clinica e in Laboratorio
Issue number2
Publication statusPublished - Apr 1986


  • Cryoprecipitation
  • Essential mixed cryoglobulinemia
  • Fibrin
  • Fibrinogen
  • Fibrinogen degradation products
  • Fibronectin

ASJC Scopus subject areas

  • Clinical Biochemistry


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