Fibrous Dysplasia of the Rib Mimicking a Malignant Bone Tumor at SPECT/CT with 99mTc-MDP

Ludovic Fournel, Cristian Rapicetta, Alessandro Fraternali, Salvatore Bellafiore, Massimiliano Paci, Filippo Lococo

Research output: Contribution to journalArticle

Abstract

We herein report a case of a 43-year-old man with a right 8th-rib bone tumor exhibiting features of malignancy at CT-scan. Considering that a SPECT/CT with 99mTc-MDP showed solitary intense radio-tracer uptake and the inconclusive results from a fine-needle biopsy, surgical en bloc tumor resection was performed. Pathologic analysis revealed a well-limited benign bone lesion ("fibrous rib dysplasia") composed by a cellular fibrous proliferation. Since benign osseous diseases may present an intense scintigraphic tracer uptake (as in this case), we suggest a certain caution when interpreting the results of SPECT/CT with 99mTc-MDP in order to avoid misdiagnosis and wrong treatments.

Original languageEnglish
Pages (from-to)346-348
Number of pages3
JournalClinical Nuclear Medicine
Volume43
Issue number5
DOIs
Publication statusPublished - May 1 2018

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Technetium Tc 99m Medronate
Ribs
Bone and Bones
Neoplasms
Fine Needle Biopsy
Diagnostic Errors
Radio
Cell Proliferation
Single Photon Emission Computed Tomography Computed Tomography
Therapeutics

Keywords

  • osseous fibrous dysplasia
  • scintigraphy
  • SPECT/CT with Tc-MDP

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Fibrous Dysplasia of the Rib Mimicking a Malignant Bone Tumor at SPECT/CT with 99mTc-MDP. / Fournel, Ludovic; Rapicetta, Cristian; Fraternali, Alessandro; Bellafiore, Salvatore; Paci, Massimiliano; Lococo, Filippo.

In: Clinical Nuclear Medicine, Vol. 43, No. 5, 01.05.2018, p. 346-348.

Research output: Contribution to journalArticle

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