Finding the Right Partner: Science or ART?

Simona Polo, Pier Paolo Di Fiore

Research output: Contribution to journalArticlepeer-review

Abstract

In response to environmental cues, certain plasma membrane proteins are ubiquitinated, signaling their endocytosis and degradation. In the budding yeast, a single enzyme, Rsp5, is charged with this task. Lin et al. (2008) now identify an arrestin-related family of Rsp5 adaptor proteins called ARTs that confer specificity on the ubiquitination of plasma membrane proteins and contribute to the maintenance of the correct cell surface protein repertoire.

Original languageEnglish
Pages (from-to)590-592
Number of pages3
JournalCell
Volume135
Issue number4
DOIs
Publication statusPublished - Nov 14 2008

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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