Fine mapping of five human skeletal muscle genes: Alpha-tropomyosin, beta-tropomyosin, troponin-I slow-twitch, troponin-I fast-twitch, and troponin-C fast

Natascia Tiso; Luca Rampoldi; Alberto Pallavicini; Rosanna Zimbello; Davide Pandolfo; Giorgio Valle; Gerolamo Lanfranchi; Gian Antonio Danieli

doi:10.1006/bbrc.1996.5958

Fine mapping of five human skeletal muscle genes: Alpha-tropomyosin, beta-tropomyosin, troponin-I slow-twitch, troponin-I fast-twitch, and troponin-C fast

Natascia Tiso, Luca Rampoldi, Alberto Pallavicini, Rosanna Zimbello, Davide Pandolfo, Giorgio Valle, Gerolamo Lanfranchi, Gian Antonio Danieli

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

In this paper the chromosomal localization of the human skeletal muscle genes Troponin-I slow-twitch (TNNI1), Troponin-I fast-twitch (TNNI2), and Troponin-C fast (TNNC2) and the refinement of the position alpha-Tropomyosin (TPM1) and beta-Tropomyosin (TPM2) are reported. By radiation hybrid mapping, TPM1 was assigned to chromosome 15q22.1, TPM2 to chromosome 9p13.2-p13.1, TNNI1 to chromosome 1q31.3, TNNI2 to chromosome 11p15.5, and TNNC2 to chromosome 20q12-q13.11. The genomic distribution of these genes is discussed, with particular emphasis on the cluster organization of the Troponin genes.

Original language	English
Pages (from-to)	347-350
Number of pages	4
Journal	Biochemical and Biophysical Research Communications
Volume	230
Issue number	2
DOIs	https://doi.org/10.1006/bbrc.1996.5958
Publication status	Published - Jan 13 1997

ASJC Scopus subject areas

Biochemistry
Biophysics
Molecular Biology

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10.1006/bbrc.1996.5958

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Tiso, N., Rampoldi, L., Pallavicini, A., Zimbello, R., Pandolfo, D., Valle, G., Lanfranchi, G., & Danieli, G. A. (1997). Fine mapping of five human skeletal muscle genes: Alpha-tropomyosin, beta-tropomyosin, troponin-I slow-twitch, troponin-I fast-twitch, and troponin-C fast. Biochemical and Biophysical Research Communications, 230(2), 347-350. https://doi.org/10.1006/bbrc.1996.5958

Fine mapping of five human skeletal muscle genes : Alpha-tropomyosin, beta-tropomyosin, troponin-I slow-twitch, troponin-I fast-twitch, and troponin-C fast. / Tiso, Natascia; Rampoldi, Luca; Pallavicini, Alberto; Zimbello, Rosanna; Pandolfo, Davide; Valle, Giorgio; Lanfranchi, Gerolamo; Danieli, Gian Antonio.

In: Biochemical and Biophysical Research Communications, Vol. 230, No. 2, 13.01.1997, p. 347-350.

Research output: Contribution to journal › Article › peer-review

Tiso, N, Rampoldi, L, Pallavicini, A, Zimbello, R, Pandolfo, D, Valle, G, Lanfranchi, G & Danieli, GA 1997, 'Fine mapping of five human skeletal muscle genes: Alpha-tropomyosin, beta-tropomyosin, troponin-I slow-twitch, troponin-I fast-twitch, and troponin-C fast', Biochemical and Biophysical Research Communications, vol. 230, no. 2, pp. 347-350. https://doi.org/10.1006/bbrc.1996.5958

Tiso, Natascia ; Rampoldi, Luca ; Pallavicini, Alberto ; Zimbello, Rosanna ; Pandolfo, Davide ; Valle, Giorgio ; Lanfranchi, Gerolamo ; Danieli, Gian Antonio. / Fine mapping of five human skeletal muscle genes : Alpha-tropomyosin, beta-tropomyosin, troponin-I slow-twitch, troponin-I fast-twitch, and troponin-C fast. In: Biochemical and Biophysical Research Communications. 1997 ; Vol. 230, No. 2. pp. 347-350.

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abstract = "In this paper the chromosomal localization of the human skeletal muscle genes Troponin-I slow-twitch (TNNI1), Troponin-I fast-twitch (TNNI2), and Troponin-C fast (TNNC2) and the refinement of the position alpha-Tropomyosin (TPM1) and beta-Tropomyosin (TPM2) are reported. By radiation hybrid mapping, TPM1 was assigned to chromosome 15q22.1, TPM2 to chromosome 9p13.2-p13.1, TNNI1 to chromosome 1q31.3, TNNI2 to chromosome 11p15.5, and TNNC2 to chromosome 20q12-q13.11. The genomic distribution of these genes is discussed, with particular emphasis on the cluster organization of the Troponin genes.",

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