Fine needle aspiration biopsy of a granulocytic sarcoma (chloroma) of the breast

G. Pettinato, A. De Chiara, L. Insabato, A. De Renzo

Research output: Contribution to journalArticle

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Abstract

A case of granulocytic sarcoma (chloroma) presenting as an isolated left breast mass in a 56-year-old woman is described. The diagnosis was initially considered from the examination of a fine needle aspiration (FNA) biopsy specimen because of the recognition of granulocytic differentiation in the cytologic material. The patient showed no peripheral blood or bone marrow evidence of leukemia. A biopsy revealed a green neoplastic tissue infiltrating the breast. Immunohistochemical study showed intracytoplasmic lysozyme, a marker for myeloid precursors, and ultrastructural examination revealed primary myeloid granulation. These findings confirmed the FNA cytologic diagnosis of granulocytic sarcoma, which should be considered when eosinophilic myelocytes are observed in aspirated material.

Original languageEnglish
Pages (from-to)67-71
Number of pages5
JournalActa Cytologica
Volume32
Issue number1
Publication statusPublished - 1988

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Myeloid Sarcoma
Fine Needle Biopsy
Breast
Granulocyte Precursor Cells
Muramidase
Leukemia
Bone Marrow
Biopsy

ASJC Scopus subject areas

  • Cell Biology
  • Anatomy
  • Histology

Cite this

Fine needle aspiration biopsy of a granulocytic sarcoma (chloroma) of the breast. / Pettinato, G.; De Chiara, A.; Insabato, L.; De Renzo, A.

In: Acta Cytologica, Vol. 32, No. 1, 1988, p. 67-71.

Research output: Contribution to journalArticle

Pettinato, G, De Chiara, A, Insabato, L & De Renzo, A 1988, 'Fine needle aspiration biopsy of a granulocytic sarcoma (chloroma) of the breast', Acta Cytologica, vol. 32, no. 1, pp. 67-71.
Pettinato, G. ; De Chiara, A. ; Insabato, L. ; De Renzo, A. / Fine needle aspiration biopsy of a granulocytic sarcoma (chloroma) of the breast. In: Acta Cytologica. 1988 ; Vol. 32, No. 1. pp. 67-71.
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