Fine needle aspiration cytology determinants of the diagnosis of primary nodal Kaposi's sarcoma as the first sign of unknown HIV infection: A case report

Luca Morelli, Teresa Pusiol, Irene Piscioli, Franca Del Nonno, Alessia Brenna, Stefano Licci

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Kaposi's sarcoma (KS) is a vascular malignant tumor characterized by human herpesvirus 8 infection of neoplastic cells. Diffuse cutaneous lesions represent the classical clinical presentation. This case report describes the first fine needle aspiration cytology findings of a primary lymph nodal KS, a rather unusual localization of the disease. Case: A 28-year-old, apparently healthy man saw a surgeon for right inguinal node enlargement without other symptoms. The clinician performed fine needle aspiration and made a preliminary diagnosis of a neoplasm of probable mesenchymal origin, not otherwise specified. The lymph node was excised, and the final histologic diagnosis was primary lymphoadenopathic KS. A serologic test revealed antibody positivity for HIV. Conclusion: The diagnosis of primary KS of the lymph node, in the absence of any other clinical manifestation, was the first sign of HIV infection.

Original languageEnglish
Pages (from-to)602-604
Number of pages3
JournalActa Cytologica
Volume51
Issue number4
Publication statusPublished - 2007

Keywords

  • Aspiration biopsy, fine-needle
  • HIV
  • Kaposi's sarcoma
  • Lymph nodes

ASJC Scopus subject areas

  • Anatomy
  • Cell Biology
  • Histology

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