Abstract
Objective: To describe the cytopathologic findings in a case of alveolar rhabdomyosarcoma (ARMS) of the perineum in a 13-year-old girl and to compare the cytopathologic findings with the histopathologic and immunohistochemical features observed on the corresponding fragments obtained from core biopsy of the mass. Study Design: The cytopathologic findings observed in fine needle aspiration biopsy of a vulvar mass were analyzed with reference to their predictive diagnostic value in pathologic evaluation of the lesion. Results: Following a prospective cytopathologic diagnosis of ARMS, a cutting needle core biopsy was performed. Histopathologic and immunohistochemical study of the tissue fragments confirmed the cytopathologic diagnosis. Conclusion: Careful cytopathologic evaluation of optimal cell samples from ARMS may elicit a correct diagnosis provided that immunocytochemical staining for markers of myogenic differentiation is performed in a pretherapeutic phase.
| Original language | English |
|---|---|
| Pages (from-to) | 385-389 |
| Number of pages | 5 |
| Journal | Acta Cytologica |
| Volume | 51 |
| Issue number | 3 |
| Publication status | Published - 2007 |
Keywords
- Aspiration cytology, fine needle
- Neoplasms, soft tissue
- Sarcoma, pediatric
ASJC Scopus subject areas
- Anatomy
- Cell Biology
- Histology