Fine needle aspiration cytology of perineal alveolar rhabdomyosarcoma: Cytohistopathologic and immunocytochemical correlations

Franco Fulciniti, Gerardo Botti, Annarosaria De Chiara, Vincenzo Parlato, Serena Russo, Laura Vosa, Michela M. Nappi

Research output: Contribution to journalArticle

Abstract

Objective: To describe the cytopathologic findings in a case of alveolar rhabdomyosarcoma (ARMS) of the perineum in a 13-year-old girl and to compare the cytopathologic findings with the histopathologic and immunohistochemical features observed on the corresponding fragments obtained from core biopsy of the mass. Study Design: The cytopathologic findings observed in fine needle aspiration biopsy of a vulvar mass were analyzed with reference to their predictive diagnostic value in pathologic evaluation of the lesion. Results: Following a prospective cytopathologic diagnosis of ARMS, a cutting needle core biopsy was performed. Histopathologic and immunohistochemical study of the tissue fragments confirmed the cytopathologic diagnosis. Conclusion: Careful cytopathologic evaluation of optimal cell samples from ARMS may elicit a correct diagnosis provided that immunocytochemical staining for markers of myogenic differentiation is performed in a pretherapeutic phase.

Original languageEnglish
Pages (from-to)385-389
Number of pages5
JournalActa Cytologica
Volume51
Issue number3
Publication statusPublished - 2007

Keywords

  • Aspiration cytology, fine needle
  • Neoplasms, soft tissue
  • Sarcoma, pediatric

ASJC Scopus subject areas

  • Anatomy
  • Cell Biology
  • Histology

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