First clinical trial for a new CRRT machine: The Prismaflex

G. Salvatori, Z. Ricci, M. Bonello, R. Ratanarat, V. D'Intini, A. Brendolan, M. Dan, P. Piccinni, R. Bellomo, Claudio Ronco

Research output: Contribution to journalArticlepeer-review


A new CRRT machine has been designed to fulfill the expectations of nephrologists and intensivists operating in the common ground of critical care nephrology. The new equipment is called " Prismaflex" (Gambro-Dasco, Mirandola, Modena) and it is the natural evolution of the Prisma machine that has been utilized woridwide for CRRT in the last decade. We performed a preliminary "alfa trial" to establish usability, flexibility and realiability of the new device. Accuracy was also tested by recording various operational parameters during different intermittent and continuous renal replacement modalities. Forty-one runs were conducted on 13 patients and the difference between delivered and prescribed parameters was always lower than 2%. We concluded that the new Prismatlex is a well designed new machine for CRRT and can be safely and effectively utilized in the critical care nephrology setting.

Original languageEnglish
Pages (from-to)404-409
Number of pages6
JournalInternational Journal of Artificial Organs
Issue number5
Publication statusPublished - May 2004


  • Acute renal failure
  • CRRT
  • Hemofiltration
  • Prismaflex

ASJC Scopus subject areas

  • Biophysics


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