First impressions about Adherus, a new dural sealant

Research output: Contribution to journalArticle

Abstract

Purpose: The aim of the study is to report our first impressions about Adherus, a novel dural sealant, used in neurosurgical endoscopic transnasal procedures. Methods: We retrospectively reviewed the clinical and surgical records of the first 11 patients with intraoperative high-flow cerebrospinal fluid leak treated with the aid of Adherus at our center between February and October 2014. The healing at the level of the dural plasty was monitored and evaluated radiologically and with regular endoscopic inspections. Results: With a median follow-up of 210 days, no postoperative CSF leak or surgical site infections were found in any of the cases. Conclusions: Based on our preliminary experience, this new dural sealant seems to provide an effective aid in dural plasty during endoscopic transphenoidal procedures.

Original languageEnglish
Pages (from-to)e372-e375
JournalJournal of Applied Biomaterials and Functional Materials
Volume13
Issue number4
DOIs
Publication statusPublished - 2015

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Sealants
Cerebrospinal fluid
Surgical Wound Infection
Inspection

Keywords

  • Dural sealant
  • Polytheyleneimine
  • Postoperative cerebrospinal fluid leaks
  • Transphenoidal endoscopic surgery

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomedical Engineering
  • Biomaterials

Cite this

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title = "First impressions about Adherus, a new dural sealant",
abstract = "Purpose: The aim of the study is to report our first impressions about Adherus, a novel dural sealant, used in neurosurgical endoscopic transnasal procedures. Methods: We retrospectively reviewed the clinical and surgical records of the first 11 patients with intraoperative high-flow cerebrospinal fluid leak treated with the aid of Adherus at our center between February and October 2014. The healing at the level of the dural plasty was monitored and evaluated radiologically and with regular endoscopic inspections. Results: With a median follow-up of 210 days, no postoperative CSF leak or surgical site infections were found in any of the cases. Conclusions: Based on our preliminary experience, this new dural sealant seems to provide an effective aid in dural plasty during endoscopic transphenoidal procedures.",
keywords = "Dural sealant, Polytheyleneimine, Postoperative cerebrospinal fluid leaks, Transphenoidal endoscopic surgery",
author = "Cesare Zoia and Daniele Bongetta and Francesco Lombardi and Custodi, {Viola Marta} and Raffaelino Pugliese and Paolo Gaetani",
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T1 - First impressions about Adherus, a new dural sealant

AU - Zoia, Cesare

AU - Bongetta, Daniele

AU - Lombardi, Francesco

AU - Custodi, Viola Marta

AU - Pugliese, Raffaelino

AU - Gaetani, Paolo

PY - 2015

Y1 - 2015

N2 - Purpose: The aim of the study is to report our first impressions about Adherus, a novel dural sealant, used in neurosurgical endoscopic transnasal procedures. Methods: We retrospectively reviewed the clinical and surgical records of the first 11 patients with intraoperative high-flow cerebrospinal fluid leak treated with the aid of Adherus at our center between February and October 2014. The healing at the level of the dural plasty was monitored and evaluated radiologically and with regular endoscopic inspections. Results: With a median follow-up of 210 days, no postoperative CSF leak or surgical site infections were found in any of the cases. Conclusions: Based on our preliminary experience, this new dural sealant seems to provide an effective aid in dural plasty during endoscopic transphenoidal procedures.

AB - Purpose: The aim of the study is to report our first impressions about Adherus, a novel dural sealant, used in neurosurgical endoscopic transnasal procedures. Methods: We retrospectively reviewed the clinical and surgical records of the first 11 patients with intraoperative high-flow cerebrospinal fluid leak treated with the aid of Adherus at our center between February and October 2014. The healing at the level of the dural plasty was monitored and evaluated radiologically and with regular endoscopic inspections. Results: With a median follow-up of 210 days, no postoperative CSF leak or surgical site infections were found in any of the cases. Conclusions: Based on our preliminary experience, this new dural sealant seems to provide an effective aid in dural plasty during endoscopic transphenoidal procedures.

KW - Dural sealant

KW - Polytheyleneimine

KW - Postoperative cerebrospinal fluid leaks

KW - Transphenoidal endoscopic surgery

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