First-time success with needle procedures was higher with a warm lidocaine and tetracaine patch than an eutectic mixture of lidocaine and prilocaine cream

Giorgio Cozzi, Fabio Borrometi, Franca Benini, Elena Neri, Francesca Rusalen, Loredana Celentano, Davide Zanon, Silvana Schreiber, Luca Ronfani, Egidio Barbi

Research output: Contribution to journalArticlepeer-review

Abstract

Aim: More than 50% of children report apian during venepuncture or intravenous cannulation and using local anaesthetics before needle procedures can lead to different success rates. This study examined how many needle procedures were successful at the first attempt when children received either a warm lidocaine and tetracaine patch or an eutectic mixture of lidocaine and prilocaine (EMLA) cream. Methods: We conducted this multicentre randomised controlled trial at three tertiary-level children's hospitals in Italy in 2015. Children aged three to 10 years were enrolled in an emergency department, paediatric day hospital and paediatric ward and randomly allocated to receive a warm lidocaine and tetracaine patch or EMLA cream. The primary outcome was the success rate at the first attempt. Results: The analysis included 172 children who received a warm lidocaine and tetracaine patch and 167 who received an EMLA cream. The needle procedure was successful at the first attempt in 158 children (92.4%) who received the warm patch and in 142 children (85.0%) who received the cream (p = 0.03). The pain scores were similar in both groups. Conclusion: This study showed that the first-time needle procedure success was 7.4% higher in children receiving a warm lidocaine and tetracaine patch than EMLA cream.

Original languageEnglish
Pages (from-to)773-778
Number of pages6
JournalActa Paediatrica, International Journal of Paediatrics
Volume106
Issue number5
DOIs
Publication statusPublished - May 1 2017

Keywords

  • Eutectic mixture of lidocaine and tetracaine cream
  • Local anaesthetic
  • Needle procedure
  • Procedural success rate
  • Warm lidocaine and tetracaine patch

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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