First urinary tract infections in children: the role of the risk factors proposed by the Italian recommendations

I Alberici, A La Manna, M Pennesi, M Starc, F Scozzola, G Nicolini, A Toffolo, G Marra, R Chimenz, F Sica, S Maringhini, L Monasta, G Montini

Research output: Contribution to journalArticle

Abstract

AIM: In 2009, the Italian society for paediatric nephrology suggested the need for cystography, following a first febrile urinary tract infection (UTI), only in children at high risk for dilating vesicoureteral reflux or in the event of a second infection. The aim of this study was to evaluate the adequacy of the risk factors proposed by the Italian guidelines. METHODS: Children aged 2-36 months, managed by 10 Italian hospitals between 2009 and 2013, with a first febrile UTI were retrospectively evaluated. RESULTS: Four hundred and fourteen children were included: 51% female, mean age eight months. Escherichia coli was responsible of 84% UTIs. 269 children (65%) presented at least one risk factor, thus were further investigated: 44% had a reflux. The presence of a pathogen other than E. coli significantly predicted high-grade reflux, both in the univariate (Odd Ratio 2.52, 95% Confidence Interval 1.32-4.81, p 
Original languageEnglish
Pages (from-to)544-550
Number of pages7
JournalActa Paediatrica, International Journal of Paediatrics
Volume108
Issue number3
DOIs
Publication statusPublished - Mar 2019

Keywords

  • *Guidelines
  • *Urinary tract infection
  • *Vesicoureteral reflux

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