Five-year results of thoracic endovascular aortic repair with the Zenith TX2

Jon S. Matsumura, Germano Melissano, Richard P. Cambria, Michael D. Dake, Shraddha Mehta, Lars G. Svensson, Randy D. Moore

Research output: Contribution to journalArticlepeer-review


Background This trial evaluated thoracic endovascular aortic repair (TEVAR) compared with open surgical repair of descending thoracic aortic aneurysms and large ulcers at 42 international sites. Whereas several studies demonstrate early safety and utility advantages with TEVAR, longer follow-up is important because of concerns about durability of TEVAR. Methods This prospective, nonrandomized study enrolled 160 TEVAR patients treated with the Cook Zenith TX2 and 70 open surgical repair patients. Results Although follow-up was limited, 5-year mortality rate was similar at 37% for both groups. Aneurysm-related mortality rate was 5.9% with TEVAR compared with 12% with open surgical repair (P =.11). There were no ruptures of the treated aneurysms in either group or open conversions in the TEVAR group. Predefined severe morbidity occurred at a significantly lower rate in TEVAR (21%) compared with open surgical repair (39%; P

Original languageEnglish
Pages (from-to)1-10
Number of pages10
JournalJournal of Vascular Surgery
Issue number1
Publication statusPublished - 2014

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery


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