Fixation pattern and macular sensitivity in eyes with subfoveal choroidal neovascularization secondary to age-related macular degeneration. A microperimetry study

Edoardo Midena, Pietro Paolo Radin, Elisabetta Pilotto, Alessandra Ghirlando, Enrica Convento, Monica Varano

Research output: Contribution to journalArticle

Abstract

Purpose. To investigate the effects of subfoveal choroidal neovascularizzation (CNV) secondary to age-related macular degeneration (AMD) on macular functional parameters quantified with an automatic fundus perimeter. Methods. 118 eyes of 98 consecutive patients with subfoveal CNV secondary to AMD were evaluated. Best corrected visual acuity (ETDRS charts), fundus photography, and fluorescein angiography were performed. Microperimetry (fundus-related perimetry) was used to quantify macular sensitivity and fixation pattern (location and stability). Results. Of 118 eyes: 26 (21.9%) had central, 18 (15.1%) poor central and 74 (63.0%) eccentric fixation; 31 (26.0%) had stable, 42 (35.6%) relatively unstable and 45 (38.4%) unstable fixation. In 75 eyes (63.4%) a dense central scotoma was found. Angiographic classification of subfoveal CNV (occult versus classic) was not significantly related to fixation pattern (location: P = 0.274; stability: P = 0.385), and presence of dense scotoma (P = 0.41). Conclusion. Microperimetric quantification of macular sensitivity and fixation pattern in eyes with subfoveal CNV secondary to AMD offers new data about the impact of visual impairment in these eyes. Moreover, microperimetry improves the functional evaluation of subfoveal CNV in AMD.

Original languageEnglish
Pages (from-to)55-61
Number of pages7
JournalSeminars in Ophthalmology
Volume19
Issue number1-2
DOIs
Publication statusPublished - Mar 2004

Keywords

  • Age related macular degeneration
  • Microperimetry
  • Retinal fixation
  • Subfoveal choroidal neovascularization
  • Visual impairment

ASJC Scopus subject areas

  • Ophthalmology

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