Flow Cytometry and T-Cell Response Monitoring after Smallpox Vaccination

Fabrizio Poccia, Cristiana Gioia, Carla Montesano, Federico Martini, Douglas Horejsh, Concetta Castilletti, Leopoldo Paolo Pucillo, Maria Rosaria Capobianchi, Giuseppe Ippolito

Research output: Contribution to journalArticle

Abstract

Orthopoxvirus zoonosis or smallpox as result of bioterrorism or biological warfare represents a risk for epidemic spread. By monitoring T-cell responses by flow cytometry, we observed a recall response after recent vaccination against smallpox. When the high similarity between the orthopoxviruses is considered, this rapid assay that uses vaccinia antigens could identify recently exposures.

Original languageEnglish
Pages (from-to)1468-1470
Number of pages3
JournalEmerging Infectious Diseases
Volume9
Issue number11
Publication statusPublished - Nov 2003

ASJC Scopus subject areas

  • Microbiology (medical)

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