Abstract
Acute generalized exanthematous pustulosis (AGEP) is a severe cutaneous adverse reaction and is usually caused by drugs. It is characterized by fever and acute, extensive occurrence of disseminated sterile pustules, accompanied by fever, malaise and peripheral blood leucocytosis. There have been several reports to date of AGEP following exposure to antifungals. In particular, terbinafine is included in the list of the agents conferring the highest risk of AGEP. The authors report the case of a 70-year-old male patient who developed AGEP shortly after commencing treatment with fluconazole, which has been reported in association with AGEP in a single case report. To our knowledge, this is the first reported case of AGEP associated with positive fluconazole patch test.
| Original language | English |
|---|---|
| Pages (from-to) | 212 |
| Number of pages | 1 |
| Journal | Indian Journal of Dermatology |
| Volume | 60 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Apr 1 2015 |
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Keywords
- Antifungals
- drug
- patch test
- reaction
- skin
ASJC Scopus subject areas
- Dermatology
Cite this
Fluconazole-induced acute generalized exanthematous pustulosis. / Di Lernia, Vito; Ricci, Cinzia.
In: Indian Journal of Dermatology, Vol. 60, No. 2, 01.04.2015, p. 212.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Fluconazole-induced acute generalized exanthematous pustulosis
AU - Di Lernia, Vito
AU - Ricci, Cinzia
PY - 2015/4/1
Y1 - 2015/4/1
N2 - Acute generalized exanthematous pustulosis (AGEP) is a severe cutaneous adverse reaction and is usually caused by drugs. It is characterized by fever and acute, extensive occurrence of disseminated sterile pustules, accompanied by fever, malaise and peripheral blood leucocytosis. There have been several reports to date of AGEP following exposure to antifungals. In particular, terbinafine is included in the list of the agents conferring the highest risk of AGEP. The authors report the case of a 70-year-old male patient who developed AGEP shortly after commencing treatment with fluconazole, which has been reported in association with AGEP in a single case report. To our knowledge, this is the first reported case of AGEP associated with positive fluconazole patch test.
AB - Acute generalized exanthematous pustulosis (AGEP) is a severe cutaneous adverse reaction and is usually caused by drugs. It is characterized by fever and acute, extensive occurrence of disseminated sterile pustules, accompanied by fever, malaise and peripheral blood leucocytosis. There have been several reports to date of AGEP following exposure to antifungals. In particular, terbinafine is included in the list of the agents conferring the highest risk of AGEP. The authors report the case of a 70-year-old male patient who developed AGEP shortly after commencing treatment with fluconazole, which has been reported in association with AGEP in a single case report. To our knowledge, this is the first reported case of AGEP associated with positive fluconazole patch test.
KW - Antifungals
KW - drug
KW - patch test
KW - reaction
KW - skin
UR - http://www.scopus.com/inward/record.url?scp=84925444991&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84925444991&partnerID=8YFLogxK
U2 - 10.4103/0019-5154.152572
DO - 10.4103/0019-5154.152572
M3 - Article
AN - SCOPUS:84925444991
VL - 60
SP - 212
JO - Indian Journal of Dermatology
JF - Indian Journal of Dermatology
SN - 0019-5154
IS - 2
ER -