Abstract
PURPOSE. To assess whether fluorescein angiography (FA) alone without indocyanine green angiography (ICGA) can identify and localize occult choroidal neovascularization (CNV) in age-related macular degeneration (ARMD). METHODS. Seventy-nine eyes of 77 consecutive patients with occult CNV were evaluated independently by two skilled physicians at first with FA alone and then with FA combined with ICGA by fundus camera. RESULTS. The agreement between FA and ICGA was 73% and 68% for the two physicians (K=0.585 and 0.512, respectively). The first operator correctly identified 20/27 as plaque CNV; six had different sizes and locations. The second operator identified 25/30, with one mistaken for size and location. For focal CNV the first operator identified 34/39, and the second one 23/35. CONCLUSIONS. Comparing the FA results with ICGA, CNV was correctly identified in about 60% of cases. Therefore, ICGA should be considered an indispensable diagnostic test to identify the presence, the type, and the location of occult CNV.
| Original language | English |
|---|---|
| Pages (from-to) | 759-763 |
| Number of pages | 5 |
| Journal | European Journal of Ophthalmology |
| Volume | 15 |
| Issue number | 6 |
| Publication status | Published - Nov 2005 |
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Keywords
- Age-related macular degeneration
- Fluorescein angiography
- Indocyanine green angiography
- Occult CNV
ASJC Scopus subject areas
- Ophthalmology
Cite this
Fluorescein angiography and indocyanine green angiography for identifying occult choroidal neovascularization in age-related macular degeneration. / Pece, Alfredo; Sannace, C.; Menchini, U.; Virgili, G.; Galli, L.; Isola, V.; Brancato, R.
In: European Journal of Ophthalmology, Vol. 15, No. 6, 11.2005, p. 759-763.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Fluorescein angiography and indocyanine green angiography for identifying occult choroidal neovascularization in age-related macular degeneration
AU - Pece, Alfredo
AU - Sannace, C.
AU - Menchini, U.
AU - Virgili, G.
AU - Galli, L.
AU - Isola, V.
AU - Brancato, R.
PY - 2005/11
Y1 - 2005/11
N2 - PURPOSE. To assess whether fluorescein angiography (FA) alone without indocyanine green angiography (ICGA) can identify and localize occult choroidal neovascularization (CNV) in age-related macular degeneration (ARMD). METHODS. Seventy-nine eyes of 77 consecutive patients with occult CNV were evaluated independently by two skilled physicians at first with FA alone and then with FA combined with ICGA by fundus camera. RESULTS. The agreement between FA and ICGA was 73% and 68% for the two physicians (K=0.585 and 0.512, respectively). The first operator correctly identified 20/27 as plaque CNV; six had different sizes and locations. The second operator identified 25/30, with one mistaken for size and location. For focal CNV the first operator identified 34/39, and the second one 23/35. CONCLUSIONS. Comparing the FA results with ICGA, CNV was correctly identified in about 60% of cases. Therefore, ICGA should be considered an indispensable diagnostic test to identify the presence, the type, and the location of occult CNV.
AB - PURPOSE. To assess whether fluorescein angiography (FA) alone without indocyanine green angiography (ICGA) can identify and localize occult choroidal neovascularization (CNV) in age-related macular degeneration (ARMD). METHODS. Seventy-nine eyes of 77 consecutive patients with occult CNV were evaluated independently by two skilled physicians at first with FA alone and then with FA combined with ICGA by fundus camera. RESULTS. The agreement between FA and ICGA was 73% and 68% for the two physicians (K=0.585 and 0.512, respectively). The first operator correctly identified 20/27 as plaque CNV; six had different sizes and locations. The second operator identified 25/30, with one mistaken for size and location. For focal CNV the first operator identified 34/39, and the second one 23/35. CONCLUSIONS. Comparing the FA results with ICGA, CNV was correctly identified in about 60% of cases. Therefore, ICGA should be considered an indispensable diagnostic test to identify the presence, the type, and the location of occult CNV.
KW - Age-related macular degeneration
KW - Fluorescein angiography
KW - Indocyanine green angiography
KW - Occult CNV
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UR - http://www.scopus.com/inward/citedby.url?scp=30444450585&partnerID=8YFLogxK
M3 - Article
C2 - 16329062
AN - SCOPUS:30444450585
VL - 15
SP - 759
EP - 763
JO - European Journal of Ophthalmology
JF - European Journal of Ophthalmology
SN - 1120-6721
IS - 6
ER -