Flushing in rosacea

A possible mechanism

Marcella Guarrera, Aurora Parodi, Carla Cipriani, Carla Divano, Alfredo Rebora

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Flushing in rosacea has been investigated by means of (a) pharmacological inhibition of some possible chemical mediators and (b) titration of bradykinin as a possible effector directly in the blood. Clonidine-inhibited flushing was seen in all patients (mean 45%), other drugs had poorer results. Bradykinin increased in all patients at the climax of flushing (mean 60%). These findings support the hypothesis that epinephrine promotes a bradykinin release responsible for vasodilation.

Original languageEnglish
Pages (from-to)311-316
Number of pages6
JournalArchives of Dermatological Research
Volume272
Issue number3-4
DOIs
Publication statusPublished - Sep 1982

Fingerprint

Rosacea
Bradykinin
Clonidine
Vasodilation
Epinephrine
Pharmacology
Pharmaceutical Preparations

Keywords

  • Bradykinin
  • Clonidine
  • Epinephrine
  • Flush
  • Rosacea

ASJC Scopus subject areas

  • Dermatology

Cite this

Guarrera, M., Parodi, A., Cipriani, C., Divano, C., & Rebora, A. (1982). Flushing in rosacea: A possible mechanism. Archives of Dermatological Research, 272(3-4), 311-316. https://doi.org/10.1007/BF00509061

Flushing in rosacea : A possible mechanism. / Guarrera, Marcella; Parodi, Aurora; Cipriani, Carla; Divano, Carla; Rebora, Alfredo.

In: Archives of Dermatological Research, Vol. 272, No. 3-4, 09.1982, p. 311-316.

Research output: Contribution to journalArticle

Guarrera, M, Parodi, A, Cipriani, C, Divano, C & Rebora, A 1982, 'Flushing in rosacea: A possible mechanism', Archives of Dermatological Research, vol. 272, no. 3-4, pp. 311-316. https://doi.org/10.1007/BF00509061
Guarrera, Marcella ; Parodi, Aurora ; Cipriani, Carla ; Divano, Carla ; Rebora, Alfredo. / Flushing in rosacea : A possible mechanism. In: Archives of Dermatological Research. 1982 ; Vol. 272, No. 3-4. pp. 311-316.
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