Fluvoxamine alone in the treatment of delusional depression

Flavia Gatti, Laura Bellini, Mariangela Gasperini, Jorge Perez, Raffaella Zanardi, Enrico Smeraldi

Research output: Contribution to journalArticle

Abstract

Objective: The aim of this study was to evaluate the efficacy of fluvoxamine in the treatment of delusional depression. Method: Fifty-nine inpatients who met the DSM-III-R criteria for major depression with psychotic features were treated with fluvoxamine for 6 weeks. Patients were assessed at baseline and weekly thereafter with the Hamilton Depression Rating Scale and the Dimensions of Delusional Experience rating scale. Results: Of the 57 subjects who completed the trial, 84.2% (N=48) recovered. The index episodes of the patients who did not respond to fluvoxamine were of significantly longer duration than those of the responders. Conclusions: Fluvoxamine has a response rate similar to that of the currently most efficacious treatments for delusional depression, including antidepressants plus antipsychotics and ECT.

Original languageEnglish
Pages (from-to)414-416
Number of pages3
JournalAmerican Journal of Psychiatry
Volume153
Issue number3
Publication statusPublished - Mar 1996

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Fluvoxamine
Therapeutics
Diagnostic and Statistical Manual of Mental Disorders
Antidepressive Agents
Antipsychotic Agents
Inpatients

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Gatti, F., Bellini, L., Gasperini, M., Perez, J., Zanardi, R., & Smeraldi, E. (1996). Fluvoxamine alone in the treatment of delusional depression. American Journal of Psychiatry, 153(3), 414-416.

Fluvoxamine alone in the treatment of delusional depression. / Gatti, Flavia; Bellini, Laura; Gasperini, Mariangela; Perez, Jorge; Zanardi, Raffaella; Smeraldi, Enrico.

In: American Journal of Psychiatry, Vol. 153, No. 3, 03.1996, p. 414-416.

Research output: Contribution to journalArticle

Gatti, F, Bellini, L, Gasperini, M, Perez, J, Zanardi, R & Smeraldi, E 1996, 'Fluvoxamine alone in the treatment of delusional depression', American Journal of Psychiatry, vol. 153, no. 3, pp. 414-416.
Gatti F, Bellini L, Gasperini M, Perez J, Zanardi R, Smeraldi E. Fluvoxamine alone in the treatment of delusional depression. American Journal of Psychiatry. 1996 Mar;153(3):414-416.
Gatti, Flavia ; Bellini, Laura ; Gasperini, Mariangela ; Perez, Jorge ; Zanardi, Raffaella ; Smeraldi, Enrico. / Fluvoxamine alone in the treatment of delusional depression. In: American Journal of Psychiatry. 1996 ; Vol. 153, No. 3. pp. 414-416.
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