FMRI brain-computer interface: A tool for neuroscientific research and treatment

Ranganatha Sitaram, Andrea Caria, Ralf Veit, Tilman Gaber, Giuseppina Rota, Andrea Kuebler, Niels Birbaumer

Research output: Contribution to journalArticlepeer-review


Brain-computer interfaces based on functional magnetic resonance imaging (fMRI-BCI) allow volitional control of anatomically specific regions of the brain. Technological advancement in higher field MRI scanners, fast data acquisition sequences, preprocessing algorithms, and robust statistical analysis are anticipated to make fMRI-BCI more widely available and applicable. This noninvasive technique could potentially complement the traditional neuroscientific experimental methods by varying the activity of the neural substrates of a region of interest as an independent variable to study its effects on behavior. If the neurobiological basis of a disorder (e.g., chronic pain, motor diseases, psychopathy, social phobia, depression) is known in terms of abnormal activity in certain regions of the brain, fMRI-BCI can be targeted to modify activity in those regions with high specificity for treatment. In this paper, we review recent results of the application of fMRI-BCI to neuroscientific research and psychophysiological treatment.

Original languageEnglish
Article number25487
JournalComputational Intelligence and Neuroscience
Publication statusPublished - 2007

ASJC Scopus subject areas

  • Computer Science(all)
  • Mathematics(all)
  • Neuroscience(all)


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