ANOMALIE FOCALI DELLO SVILUPPO CORTICALE ED EPILESSIA: ASPETTI ELETTROCLINICI NELLE MALFORMAZIONI OPERCOLARI BILATERALI

Translated title of the contribution: Focal anomalies of the cortical development and epilepsy: Electroclinical features in the bilateral opercular malformations

R. Guerrini, C. Dravet, A. Battaglia, M. Bureau, J. Roger, C. Raybaud, L. De Pasquale, P. Santanelli, F. Fasano, M. O. Livet, G. Colicchio

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The advanced imaging techniques, particularly MRI, have very much contributed over the last few years to the detection, during life, of structural brain lesions underlying human epilepsy. We studied 9 patients who showed bilateral opercular and/or insular gyration anomalies on MRI. 8 of 9 patients had pseudobulbar palsy (5 'cortical' and 3 'central'), with oromotor incoordination, developmental delay, and varying degrees of mental retardation. Epilepsy was present in all but one case; had a variable age of onset, and a linear evolution in each case: either drug-resistant or well controlled right from the beginning. 4 patients showed drug-resistant seizures with falls; with focal and diffuse EEG abnormalities. Anterior corpus callosotomy in one patient helped the intractable seizures. The other 4 epilepsy cases are well controlled on AEDs.

Original languageItalian
Pages (from-to)109-111
Number of pages3
JournalBollettino - Lega Italiana contro l'Epilessia
Issue number70-71
Publication statusPublished - 1990

Fingerprint

Epilepsy
Seizures
Pseudobulbar Palsy
Ataxia
Age of Onset
Intellectual Disability
Pharmaceutical Preparations
Electroencephalography
Brain

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

ANOMALIE FOCALI DELLO SVILUPPO CORTICALE ED EPILESSIA : ASPETTI ELETTROCLINICI NELLE MALFORMAZIONI OPERCOLARI BILATERALI. / Guerrini, R.; Dravet, C.; Battaglia, A.; Bureau, M.; Roger, J.; Raybaud, C.; De Pasquale, L.; Santanelli, P.; Fasano, F.; Livet, M. O.; Colicchio, G.

In: Bollettino - Lega Italiana contro l'Epilessia, No. 70-71, 1990, p. 109-111.

Research output: Contribution to journalArticle

Guerrini, R, Dravet, C, Battaglia, A, Bureau, M, Roger, J, Raybaud, C, De Pasquale, L, Santanelli, P, Fasano, F, Livet, MO & Colicchio, G 1990, 'ANOMALIE FOCALI DELLO SVILUPPO CORTICALE ED EPILESSIA: ASPETTI ELETTROCLINICI NELLE MALFORMAZIONI OPERCOLARI BILATERALI', Bollettino - Lega Italiana contro l'Epilessia, no. 70-71, pp. 109-111.
Guerrini, R. ; Dravet, C. ; Battaglia, A. ; Bureau, M. ; Roger, J. ; Raybaud, C. ; De Pasquale, L. ; Santanelli, P. ; Fasano, F. ; Livet, M. O. ; Colicchio, G. / ANOMALIE FOCALI DELLO SVILUPPO CORTICALE ED EPILESSIA : ASPETTI ELETTROCLINICI NELLE MALFORMAZIONI OPERCOLARI BILATERALI. In: Bollettino - Lega Italiana contro l'Epilessia. 1990 ; No. 70-71. pp. 109-111.
@article{5e7981ffbaf04bdcb87663e074106a2f,
title = "ANOMALIE FOCALI DELLO SVILUPPO CORTICALE ED EPILESSIA: ASPETTI ELETTROCLINICI NELLE MALFORMAZIONI OPERCOLARI BILATERALI",
abstract = "The advanced imaging techniques, particularly MRI, have very much contributed over the last few years to the detection, during life, of structural brain lesions underlying human epilepsy. We studied 9 patients who showed bilateral opercular and/or insular gyration anomalies on MRI. 8 of 9 patients had pseudobulbar palsy (5 'cortical' and 3 'central'), with oromotor incoordination, developmental delay, and varying degrees of mental retardation. Epilepsy was present in all but one case; had a variable age of onset, and a linear evolution in each case: either drug-resistant or well controlled right from the beginning. 4 patients showed drug-resistant seizures with falls; with focal and diffuse EEG abnormalities. Anterior corpus callosotomy in one patient helped the intractable seizures. The other 4 epilepsy cases are well controlled on AEDs.",
author = "R. Guerrini and C. Dravet and A. Battaglia and M. Bureau and J. Roger and C. Raybaud and {De Pasquale}, L. and P. Santanelli and F. Fasano and Livet, {M. O.} and G. Colicchio",
year = "1990",
language = "Italian",
pages = "109--111",
journal = "Bollettino - Lega Italiana contro l'Epilessia",
issn = "0394-560X",
publisher = "Lega Italiana contro l'Epilessia",
number = "70-71",

}

TY - JOUR

T1 - ANOMALIE FOCALI DELLO SVILUPPO CORTICALE ED EPILESSIA

T2 - ASPETTI ELETTROCLINICI NELLE MALFORMAZIONI OPERCOLARI BILATERALI

AU - Guerrini, R.

AU - Dravet, C.

AU - Battaglia, A.

AU - Bureau, M.

AU - Roger, J.

AU - Raybaud, C.

AU - De Pasquale, L.

AU - Santanelli, P.

AU - Fasano, F.

AU - Livet, M. O.

AU - Colicchio, G.

PY - 1990

Y1 - 1990

N2 - The advanced imaging techniques, particularly MRI, have very much contributed over the last few years to the detection, during life, of structural brain lesions underlying human epilepsy. We studied 9 patients who showed bilateral opercular and/or insular gyration anomalies on MRI. 8 of 9 patients had pseudobulbar palsy (5 'cortical' and 3 'central'), with oromotor incoordination, developmental delay, and varying degrees of mental retardation. Epilepsy was present in all but one case; had a variable age of onset, and a linear evolution in each case: either drug-resistant or well controlled right from the beginning. 4 patients showed drug-resistant seizures with falls; with focal and diffuse EEG abnormalities. Anterior corpus callosotomy in one patient helped the intractable seizures. The other 4 epilepsy cases are well controlled on AEDs.

AB - The advanced imaging techniques, particularly MRI, have very much contributed over the last few years to the detection, during life, of structural brain lesions underlying human epilepsy. We studied 9 patients who showed bilateral opercular and/or insular gyration anomalies on MRI. 8 of 9 patients had pseudobulbar palsy (5 'cortical' and 3 'central'), with oromotor incoordination, developmental delay, and varying degrees of mental retardation. Epilepsy was present in all but one case; had a variable age of onset, and a linear evolution in each case: either drug-resistant or well controlled right from the beginning. 4 patients showed drug-resistant seizures with falls; with focal and diffuse EEG abnormalities. Anterior corpus callosotomy in one patient helped the intractable seizures. The other 4 epilepsy cases are well controlled on AEDs.

UR - http://www.scopus.com/inward/record.url?scp=0025226869&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025226869&partnerID=8YFLogxK

M3 - Articolo

AN - SCOPUS:0025226869

SP - 109

EP - 111

JO - Bollettino - Lega Italiana contro l'Epilessia

JF - Bollettino - Lega Italiana contro l'Epilessia

SN - 0394-560X

IS - 70-71

ER -