Focal cerebral infarction in newborn: Description of three cases

S. Domizio, G. M D Sabatino, A. Albanese, E. Barbante, C. Puglielli, M. Di Giannantonio, R. Quartesan, R. Domizio, Giuseppe Sabatino

Research output: Contribution to journalArticlepeer-review


We observed 3 full-term newborns with focal ischemic injury of the middle cerebral artery (MCA), in which diagnosis of MCA stroke was suspected by US and confirmed by CT scan and MRI. A four-year follow-up was carried out to study the effect of neonatal stroke on neurodevelopmental outcome. All children had a history of pre-perinatal risk factors: neonatal cerebral infarction in term infants, in fact, has many possible causes, including bacterial meningitis, inherited or acquired coagulopathies, trauma and hypoxia-ischemia. The prognosis of neonatal MCA infarction depends on early diagnosis, on the CNS plasticity mechanism and, finally, on medical therapy and neuropsychological rehabilitation.

Original languageEnglish
Pages (from-to)141-146
Number of pages6
JournalEuropean Journal of Inflammation
Issue number3
Publication statusPublished - Sep 2004


  • Cerebral artery disease
  • Cerebral ischemia
  • Middle cerebral artery
  • Newborn

ASJC Scopus subject areas

  • Immunology


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