Abstract
Introduction: This study aims to review the magnetic resonance imaging (MRI) aspects of a large series of patients with focal cortical dysplasia type II (FCD II) and attempt to identify distinctive features in the two histopathological subtypes IIa and IIb. Methods: We retrospectively reviewed the MRI scans of 118 patients with histological proven FCD IIa (n∈=∈37) or IIb (n∈=∈81) who were surgically treated for intractable epilepsy. Results: MRI was abnormal in 93 patients (79 %) and unremarkable in 25 (21 %). A dysplastic lesion was identified in 90 cases (97 %) and classified as FCD II in 83 and FCD non-II in seven cases. In three cases, the MRI diagnosis was other than FCD. There was a significant association between the presence of cortical thickening (p∈=∈0.002) and the transmantle sign (p∈
| Original language | English |
|---|---|
| Pages (from-to) | 1065-1077 |
| Number of pages | 13 |
| Journal | Neuroradiology |
| Volume | 54 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - Oct 2012 |
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Keywords
- Epilepsy
- Focal cortical dysplasia type IIa and IIb
- MRI imaging
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Clinical Neurology
- Cardiology and Cardiovascular Medicine
Cite this
Focal cortical dysplasia type IIa and IIb : MRI aspects in 118 cases proven by histopathology. / Colombo, Nadia; Tassi, Laura; Deleo, Francesco; Citterio, Alberto; Bramerio, Manuela; Mai, Roberto; Sartori, Ivana; Cardinale, Francesco; Lo Russo, Giorgio; Spreafico, Roberto.
In: Neuroradiology, Vol. 54, No. 10, 10.2012, p. 1065-1077.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Focal cortical dysplasia type IIa and IIb
T2 - MRI aspects in 118 cases proven by histopathology
AU - Colombo, Nadia
AU - Tassi, Laura
AU - Deleo, Francesco
AU - Citterio, Alberto
AU - Bramerio, Manuela
AU - Mai, Roberto
AU - Sartori, Ivana
AU - Cardinale, Francesco
AU - Lo Russo, Giorgio
AU - Spreafico, Roberto
PY - 2012/10
Y1 - 2012/10
N2 - Introduction: This study aims to review the magnetic resonance imaging (MRI) aspects of a large series of patients with focal cortical dysplasia type II (FCD II) and attempt to identify distinctive features in the two histopathological subtypes IIa and IIb. Methods: We retrospectively reviewed the MRI scans of 118 patients with histological proven FCD IIa (n∈=∈37) or IIb (n∈=∈81) who were surgically treated for intractable epilepsy. Results: MRI was abnormal in 93 patients (79 %) and unremarkable in 25 (21 %). A dysplastic lesion was identified in 90 cases (97 %) and classified as FCD II in 83 and FCD non-II in seven cases. In three cases, the MRI diagnosis was other than FCD. There was a significant association between the presence of cortical thickening (p∈=∈0.002) and the transmantle sign (p∈
AB - Introduction: This study aims to review the magnetic resonance imaging (MRI) aspects of a large series of patients with focal cortical dysplasia type II (FCD II) and attempt to identify distinctive features in the two histopathological subtypes IIa and IIb. Methods: We retrospectively reviewed the MRI scans of 118 patients with histological proven FCD IIa (n∈=∈37) or IIb (n∈=∈81) who were surgically treated for intractable epilepsy. Results: MRI was abnormal in 93 patients (79 %) and unremarkable in 25 (21 %). A dysplastic lesion was identified in 90 cases (97 %) and classified as FCD II in 83 and FCD non-II in seven cases. In three cases, the MRI diagnosis was other than FCD. There was a significant association between the presence of cortical thickening (p∈=∈0.002) and the transmantle sign (p∈
KW - Epilepsy
KW - Focal cortical dysplasia type IIa and IIb
KW - MRI imaging
UR - http://www.scopus.com/inward/record.url?scp=84867882945&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84867882945&partnerID=8YFLogxK
U2 - 10.1007/s00234-012-1049-1
DO - 10.1007/s00234-012-1049-1
M3 - Article
VL - 54
SP - 1065
EP - 1077
JO - Neuroradiology
JF - Neuroradiology
SN - 0028-3940
IS - 10
ER -