Focal epilepsy associated with dysembryoplastic neuroepithelial tumor in the area of the caudate nucleus

Marco Giulioni, Guido Rubboli, Gianluca Marucci, Matteo Martinoni, Anna Federica Marliani, Patrizia Riguzzi, Fabio Calbucci

Research output: Contribution to journalArticle

Abstract

Dysembryoplastic neuroepithelial tumors (DNTs) are usually located within the supratentorial cortex, often in the temporal lobe and they are frequently associated with intractable complex partial seizures. DNTs in extracortical sites are rare. Thus far, 21 cases of 36 DNT-lesions occurring in these areas have been reported; only 8 out of them had epilepsy. We report a case of a 39-year-old woman who had pharmacoresistant epilepsy associated to a DNT in the caudate nucleus-periventricular area treated by lesionectomy. During a 4-year follow-up period, the patient was seizure free and the tumor did not recur. We discuss the hypothetical epileptogenic mechanism involved and we review the pertinent literature.

Original languageEnglish
Pages (from-to)1119-1122
Number of pages4
JournalClinical Neurology and Neurosurgery
Volume114
Issue number8
DOIs
Publication statusPublished - Oct 2012

    Fingerprint

Keywords

  • Caudate nucleus
  • Dysembryoplastic neuroepithelial tumor
  • Epilepsy surgery
  • Glioneuronal tumors
  • Lesionectomy
  • Pharmacoresistant epilepsy

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this