Focal extra-axial hemorrahagic mass with subdural hemorrhage secondary to extramedullar hematopoiesis in idiopathic myelodysplastic syndrome

A. Di Lieva, E. Aimar, F. Tancioni, D. Levi, A. Debernardi, P. Pisano, D. Rahal, A. Nozza, M. Magagnoli, P. Gaetani

Research output: Contribution to journalArticle

Abstract

Idiopathic myelodysplastic syndrome is a disease characterized by a clonal stem cell disorder in which megacaryocitic and granulocytic lineages are mainly involved; extramedullary myeloid metaplasia is due to abnormal location of myeloid tissue in other organs than bone marrow. Rarely the central nervous system is involved. When it happens, it is typical to find masses around the brain and pachymeningeal thickening, but it is very rare to find it associated with subdural haemorrhage, as in the case we describe in the present article. Considering our case and the literature we can suggest that radiological images associated with the clinical history of the patient suggestive for extramedullary hematopoiesis can be sufficient for a correct diagnosis and for a radiotherapy treatment, demanding surgery in the case of diagnostic doubts, massive hemorrahages or neurological decifits caused by the focal lesions.

Original languageEnglish
Pages (from-to)29-32
Number of pages4
JournalJournal of Neurosurgical Sciences
Volume51
Issue number1
Publication statusPublished - Mar 2007

Keywords

  • Extramedullary hematopoiesis
  • Myelodysplastic syndrome
  • Subdural hemorrhage

ASJC Scopus subject areas

  • Clinical Neurology

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    Di Lieva, A., Aimar, E., Tancioni, F., Levi, D., Debernardi, A., Pisano, P., Rahal, D., Nozza, A., Magagnoli, M., & Gaetani, P. (2007). Focal extra-axial hemorrahagic mass with subdural hemorrhage secondary to extramedullar hematopoiesis in idiopathic myelodysplastic syndrome. Journal of Neurosurgical Sciences, 51(1), 29-32.