Abstract
The relationships between GH system and hypothalamic-pituitary-thyroid axis are complex and not yet fully understood. The reported effects of GH administration on thyroid status of GHD patients have been remarkably divergent. This review will focus on the main studies aimed to clarify the effects of GH on thyroid function, firstly going through the diagnosis of central hypothyroidism and its possible pitfalls, then elucidating the possible contexts in which GHD may develop and examining the proposed mechanisms at the basis of interactions between the GH-IGF-I system and the hypothalamic-pituitary-thyroid axis.
| Original language | English |
|---|---|
| Pages (from-to) | 71-78 |
| Number of pages | 8 |
| Journal | Best Practice and Research in Clinical Endocrinology and Metabolism |
| Volume | 31 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Feb 2017 |
Keywords
- Female
- Hormone Replacement Therapy
- Human Growth Hormone
- Humans
- Hypothalamo-Hypophyseal System
- Hypothyroidism
- Insulin-Like Growth Factor I
- Male
- Pituitary Hormones
- Thyroid Gland
- Journal Article
- Review
Fingerprint Dive into the research topics of 'Focus on GH deficiency and thyroid function'. Together they form a unique fingerprint.
Cite this
Giavoli, C., Profka, E., Rodari, G., Lania, A., & Beck-Peccoz, P. (2017). Focus on GH deficiency and thyroid function. Best Practice and Research in Clinical Endocrinology and Metabolism, 31(1), 71-78. https://doi.org/10.1016/j.beem.2017.02.003