Focus on the cetirizine use in clinical practice: A reappraisal 30 years later

Angelo G. Corsico, Salvatore Leonardi, Amelia Licari, Gianluigi Marseglia, Michele Miraglia Del Giudice, Diego G. Peroni, Carmelo Salpietro, Giorgio Ciprandi

Research output: Contribution to journalReview articlepeer-review


Antihistamines are currently one of the most commonly administered categories of drugs. They are used to treat symptoms that are secondary to histamine release, which is typical of certain allergic conditions, including rhinitis, conjunctivitis, asthma, urticaria, and anaphylaxis. Cetirizine belongs to the second-generation family, so, it is very selective for peripheral H1 receptors, is potent and quickly relieves symptoms, exerts additional anti-allergic/anti-inflammatory effects, and is usually well-tolerated. It has been marketed 30 years ago. In these years, a remarkable body of evidence has been built. The current review provides a practical update on the use of cetirizine in clinical practice.

Original languageEnglish
Article number40
JournalMultidisciplinary Respiratory Medicine
Issue number1
Publication statusPublished - Dec 6 2019


  • Antihistamines
  • Cetirizine
  • Clinical practice
  • H1 receptors
  • Histamine

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine


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