FOLFOX2 in the treatment of advanced colorectal cancer: A comparison between elderly and middle aged patients

Massimiliano Berretta, A. Bearz, S. Frustaci, R. Talamini, D. Lombardi, L. Fratino, A. Lleshi, S. Bonanno, D. Spartà, S. Palmucci, S. Berretta, U. Tirelli

Research output: Contribution to journalArticle

Abstract

The effectiveness of chemotherapy in elderly patients is still a matter of debate. We analyzed the toxicity and efficacy of the original FOLFOX2 regimen in middle aged and elderly patients affected by metastatic colorectal cancer. Consecutive patients with metastatic CRC and measurable disease were eligible. Seventy-eight partially pretreated patients were enrolled: 58 patients were defined as middle aged (

Original languageEnglish
Pages (from-to)503-508
Number of pages6
JournalJournal of Chemotherapy
Volume20
Issue number4
Publication statusPublished - Aug 2008

Keywords

  • 5-fuorouracil
  • Colorectal cancer
  • Elderly
  • Oxaliplatin

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Infectious Diseases
  • Oncology
  • Pharmacology
  • Medicine(all)

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    Berretta, M., Bearz, A., Frustaci, S., Talamini, R., Lombardi, D., Fratino, L., Lleshi, A., Bonanno, S., Spartà, D., Palmucci, S., Berretta, S., & Tirelli, U. (2008). FOLFOX2 in the treatment of advanced colorectal cancer: A comparison between elderly and middle aged patients. Journal of Chemotherapy, 20(4), 503-508.