Follicular bisection in hair transplantation surgery

E. Raposio, F. Norat, A. Orefice, C. Capello, A. Margara, M. Faggioni, N. Vercellino, P. L. Santi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The aim of this study was to evaluate, in an in vitro model, the survival and growth rates of transversely sectioned human hair follicles to assess experimentally the soundness of this approach as a future possible method for "duplicating" available donor hair grafts in hair transplantation procedures. Furthermore, we have grafted bisected hair follicles in 11 inbred mice, in order to in vivo evaluate the soundness of this procedure. A total of 300 human anagen hair follicles were thus randomly assigned to one of the following groups: group A, cultured intact as dissected, and group B, transversely transected. Regarding the in vivo animal model, we have prepared 96 emi micrografts transplanted in the dorsum of the inbred mice. No statistically significant differences were found between the growth rate of intact follicles and of lower-half follicles, whereas a statistically significant difference was found between the growth rate of follicles from the two abovementioned groups and the growth rate of the "upper-half" follicles. In our opinion, the reported in vitro and in vivo survival rates of transected human hair follicles represent an interesting starting point in striving to augment the number of donor hairs available during a hair transplantation procedure.

Original languageEnglish
Title of host publicationProceedings of the IEEE-EMBS Special Topic Conference on Molecular, Cellular and Tissue Engineering, MCTE 2002
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages157-158
Number of pages2
ISBN (Print)0780375572, 9780780375574
DOIs
Publication statusPublished - 2002
EventIEEE-EMBS Special Topic Conference on Molecular, Cellular and Tissue Engineering, MCTE 2002 - Genoa, Italy
Duration: Jun 6 2002Jun 9 2002

Other

OtherIEEE-EMBS Special Topic Conference on Molecular, Cellular and Tissue Engineering, MCTE 2002
Country/TerritoryItaly
CityGenoa
Period6/6/026/9/02

Keywords

  • Bisection
  • Hair follicles
  • Transplantation

ASJC Scopus subject areas

  • Bioengineering
  • Medicine (miscellaneous)
  • Biomaterials
  • Biomedical Engineering
  • Biotechnology

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