TY - JOUR
T1 - Follicular cutaneous larva migrans
T2 - A report of three cases and review of the literature
AU - Veraldi, Stefano
AU - Persico, Maria Chiara
AU - Francia, Claudia
AU - Nazzaro, Gianluca
AU - Gianotti, Raffaele
PY - 2013/3
Y1 - 2013/3
N2 - Background: Hookworm-related cutaneous larva migrans (CLM) is characterized clinically by erythematous and slightly raised tracks, located especially on the feet. These tracks may be single or multiple, linear or serpiginous, more or less ramified and intertwined. The length is variable (up to many cm); the width ranges from 1 mm to 4 mm. Tracks are often accompanied by severe pruritus. Methods: Three adult Caucasian patients recently returned from trips to Malaysia and Thailand, presented with follicular CLM. The disease was characterized clinically by follicular, erythematous, small papules that were sometimes topped with vesicles or pustules, located on the buttocks. Pruritus was severe. Results: Histopathological examinations revealed a perifollicular infiltrate predominantly consisting of lymphocytes and eosinophils. All patients were successfully treated with oral albendazole (400 mg/day for seven days). In the first patient, two courses were necessary. Conclusions: Dermatologists should be aware of the existence of this rare and atypical, although emerging, clinical presentation of hookworm-related CLM.
AB - Background: Hookworm-related cutaneous larva migrans (CLM) is characterized clinically by erythematous and slightly raised tracks, located especially on the feet. These tracks may be single or multiple, linear or serpiginous, more or less ramified and intertwined. The length is variable (up to many cm); the width ranges from 1 mm to 4 mm. Tracks are often accompanied by severe pruritus. Methods: Three adult Caucasian patients recently returned from trips to Malaysia and Thailand, presented with follicular CLM. The disease was characterized clinically by follicular, erythematous, small papules that were sometimes topped with vesicles or pustules, located on the buttocks. Pruritus was severe. Results: Histopathological examinations revealed a perifollicular infiltrate predominantly consisting of lymphocytes and eosinophils. All patients were successfully treated with oral albendazole (400 mg/day for seven days). In the first patient, two courses were necessary. Conclusions: Dermatologists should be aware of the existence of this rare and atypical, although emerging, clinical presentation of hookworm-related CLM.
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U2 - 10.1111/j.1365-4632.2012.05723.x
DO - 10.1111/j.1365-4632.2012.05723.x
M3 - Article
C2 - 23414157
AN - SCOPUS:84873951247
VL - 52
SP - 327
EP - 330
JO - International Journal of Dermatology
JF - International Journal of Dermatology
SN - 0011-9059
IS - 3
ER -