TY - JOUR
T1 - Follicular lymphoma
T2 - Still Six characters in search of an author?
AU - Piccaluga, Pier Paolo
AU - Pileri, Stefano A.
AU - Agostinelli, Claudio
AU - Klapper, Wolfram
AU - Lennert, Karl
PY - 2011/9
Y1 - 2011/9
N2 - Follicular lymphoma (FL) is regarded as a distinct entity in the literature as well as in the 2008 edition of the WHO classification of tumours of haematopoietic and lymphoid tissues.Nevertheless, there are still several issues that are matters of controversy such as the grading system or the exact biological location of grade 3B FL. This makes FL somewhat like the Six characters in search of an author of Pirandello's comedy. Here, we revise the morphology and pathobiology of FL by highlighting both the areas remaining critical and future perspectives. This review was inspired by the reappraisal of Professor Lennert's personal archive that represents a unique legacy for the entire scientific community.
AB - Follicular lymphoma (FL) is regarded as a distinct entity in the literature as well as in the 2008 edition of the WHO classification of tumours of haematopoietic and lymphoid tissues.Nevertheless, there are still several issues that are matters of controversy such as the grading system or the exact biological location of grade 3B FL. This makes FL somewhat like the Six characters in search of an author of Pirandello's comedy. Here, we revise the morphology and pathobiology of FL by highlighting both the areas remaining critical and future perspectives. This review was inspired by the reappraisal of Professor Lennert's personal archive that represents a unique legacy for the entire scientific community.
KW - Follicular lymphoma
KW - germinal center B-lymphocytes
KW - molecular biology
KW - morphology
KW - phenotype
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U2 - 10.3109/10428194.2011.575493
DO - 10.3109/10428194.2011.575493
M3 - Article
C2 - 21657965
AN - SCOPUS:80052048725
VL - 52
SP - 1655
EP - 1667
JO - Leukemia and Lymphoma
JF - Leukemia and Lymphoma
SN - 1042-8194
IS - 9
ER -