Abstract
Folliculotropic mycosis fungoides is a variant of mycosis fungoides with a worse prognosis than the classic form. It can be associated with follicular mucinosis. We report a case of folliculotropic mycosis fungoides developing in the months following methotrexate therapy in a psoriatic patient. This lymphoma did not regress after stopping the antipsoriatic treatment. There is a known relationship between the use of immunosuppressive therapies and the development of lymphoproliferative malignancies. However these lymphomas are mainly B-cell non-Hodgkin lymphomas associated with Epstein-Barr virus. In our patient the short period of time from the beginning of the immunosuppressive treatment to the occurrence of the T-cell lymphoma does not support a strong causal relationship between the drug intake and the development of mycosis fungoides. To the best of our knowledge, this is the first case of folliculotropic mycosis fungoides in a patient treated with methotrexate for psoriasis.
| Original language | German |
|---|---|
| Pages (from-to) | 1068-1070 |
| Number of pages | 3 |
| Journal | JDDG - Journal of the German Society of Dermatology |
| Volume | 7 |
| Issue number | 12 |
| DOIs | |
| Publication status | Published - Dec 2009 |
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Keywords
- Cutaneous T-cell lymphoma
- Mycosis fungoides
- Psoriasis
ASJC Scopus subject areas
- Dermatology
Cite this
Follikulotrope Mycosis fungoides bei einer Patientin mit Psoriasis unter Methotrexat-Therapie. / Di Lernia, Vito; Ricci, Cinzia; Grenzi, Laura; Froio, Elisabetta; Piana, Simonetta.
In: JDDG - Journal of the German Society of Dermatology, Vol. 7, No. 12, 12.2009, p. 1068-1070.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Follikulotrope Mycosis fungoides bei einer Patientin mit Psoriasis unter Methotrexat-Therapie
AU - Di Lernia, Vito
AU - Ricci, Cinzia
AU - Grenzi, Laura
AU - Froio, Elisabetta
AU - Piana, Simonetta
PY - 2009/12
Y1 - 2009/12
N2 - Folliculotropic mycosis fungoides is a variant of mycosis fungoides with a worse prognosis than the classic form. It can be associated with follicular mucinosis. We report a case of folliculotropic mycosis fungoides developing in the months following methotrexate therapy in a psoriatic patient. This lymphoma did not regress after stopping the antipsoriatic treatment. There is a known relationship between the use of immunosuppressive therapies and the development of lymphoproliferative malignancies. However these lymphomas are mainly B-cell non-Hodgkin lymphomas associated with Epstein-Barr virus. In our patient the short period of time from the beginning of the immunosuppressive treatment to the occurrence of the T-cell lymphoma does not support a strong causal relationship between the drug intake and the development of mycosis fungoides. To the best of our knowledge, this is the first case of folliculotropic mycosis fungoides in a patient treated with methotrexate for psoriasis.
AB - Folliculotropic mycosis fungoides is a variant of mycosis fungoides with a worse prognosis than the classic form. It can be associated with follicular mucinosis. We report a case of folliculotropic mycosis fungoides developing in the months following methotrexate therapy in a psoriatic patient. This lymphoma did not regress after stopping the antipsoriatic treatment. There is a known relationship between the use of immunosuppressive therapies and the development of lymphoproliferative malignancies. However these lymphomas are mainly B-cell non-Hodgkin lymphomas associated with Epstein-Barr virus. In our patient the short period of time from the beginning of the immunosuppressive treatment to the occurrence of the T-cell lymphoma does not support a strong causal relationship between the drug intake and the development of mycosis fungoides. To the best of our knowledge, this is the first case of folliculotropic mycosis fungoides in a patient treated with methotrexate for psoriasis.
KW - Cutaneous T-cell lymphoma
KW - Mycosis fungoides
KW - Psoriasis
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UR - http://www.scopus.com/inward/citedby.url?scp=71149093075&partnerID=8YFLogxK
U2 - 10.1111/j.1610-0387.2009.07153.x
DO - 10.1111/j.1610-0387.2009.07153.x
M3 - Articolo
C2 - 19686545
AN - SCOPUS:71149093075
VL - 7
SP - 1068
EP - 1070
JO - JDDG - Journal of the German Society of Dermatology
JF - JDDG - Journal of the German Society of Dermatology
SN - 1610-0379
IS - 12
ER -